SCHEMBL3901737

SCHEMBL3901737

CC(N)CC1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL525855 1.00
SCHEMBL12262022 1.00
SCHEMBL12204090 0.97 CYP1A2 (0.37)
SCHEMBL25822676 0.97 CYP1A2 (0.37)
SCHEMBL612657 0.97 CYP1A2 (0.37)
SCHEMBL15858469 0.97 CYP1A2 (0.37)
SCHEMBL526022 0.97 CYP1A2 (0.37)
SCHEMBL14615992 0.94
SCHEMBL21765542 0.94
SCHEMBL525786 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10000555-B2 Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus SEATTLE GENETICS, INC. (US) 2018-06-19 US disclosed
EP-2795301-B1 A METHOD OF DETERMINING CATALYTIC FINES IN A FUEL OIL NANONORD AS (DK) 2018-03-21 EP disclosed
EP-3044226-B1 ARYL ETHER-BASE KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2017-09-06 EP disclosed
US-20170234883-A1 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR GENENTECH, INC. (US) 2017-08-17 US disclosed
US-20130123465-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS SEATTLE GENETICS, INC. (US) 2013-05-16 US disclosed
US-8343928-B2 Monomethylvaline compounds having phenylalanine side-chain replacements at the C-terminus SEATTLE GENETICS, INC. (US) 2013-01-01 US disclosed
US-20090181929-A1 ORGANIC COMPOUNDS KONISHI KAZUHIDE 2009-07-16 US disclosed
US-20090075968-A1 CETP inhibitors SAKAKI JUNICHI 2009-03-19 US disclosed
EP-2024356-A1 BICYCLIC DERIVATIVES AS CETP INHIBITORS Novartis AG (CH) 2009-02-18 EP disclosed
EP-2018376-A1 BENZYLAMINE DERIVATIVES AS CETP INHIBITORS Novartis Pharma AG (CH) 2009-01-28 EP disclosed
US-4076949-A REACTING ALCOHOL WITH CARBON MONOXIDE AND OXYGEN, CATALYSIS ATLANTIC RICHFIELD COMPANY (US) 1978-02-28 US disclosed
US-4069388-A Preparation of oxalate esters from carbon monoxide and an alkoxycycloalkene ATLANTIC RICHFIELD COMPANY (US) 1978-01-17 US disclosed
US-4065490-A Process for the preparation of oxalate esters from carbon monoxide and an enol ether ATLANTIC RICHFIELD COMPANY (US) 1977-12-27 US disclosed
US-4041068-A AS CATALYST A PALLADIUM, PLATINUM OR RHODIUM SALT WITH AN AMINE AND AN ALCOHOL ATLANTIC RICHFIELD COMPANY (US) 1977-08-09 US disclosed
US-4041067-A AS CATALYST A PALLADIUM, PLATINUM, RHODIUM, CADMIUM, COBALT, ZINC OR COPPER SALT WITH AN AMINE AND AN ALCOHOL ATLANTIC RICHFIELD COMPANY (US) 1977-08-09 US disclosed
US-4005131-A METAL SALT CATALYST, AMINE BASE ATLANTIC RICHFIELD COMPANY (US) 1977-01-25 US disclosed
US-4005129-A OXALATE ESTERS ATLANTIC RICHFIELD COMPANY (US) 1977-01-25 US disclosed
US-4005128-A FROM CARBON MONOXIDE AND ALCOHOL, METAL SALT CATALYST ATLANTIC RICHFIELD COMPANY (US) 1977-01-25 US disclosed
US-3992436-A Synthesis of oxalate esters from carbon monoxide and carboxylic ortho esters ATLANTIC RICHFIELD COMPANY (US) 1976-11-16 US disclosed
US-3931148-A ALKALI SOLUBLE SURFACTANT BASF WYANDOTTE CORPORATION (US) 1976-01-06 US disclosed