Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 19/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902190 | 1.00 | KCNA3 (1.00) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3895470 | 0.91 | KCNA3 (0.84) | KCNA3 | |
| SCHEMBL3895286 | 0.91 | KCNA3 (0.87) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3895291 | 0.91 | KCNA3 (0.87) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3900106 | 0.90 | KCNA3 (1.00) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3904054 | 0.90 | KCNA3 (1.00) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3894769 | 0.90 | KCNA3 (0.84) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3893625 | 0.90 | KCNA3 (1.00) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3895316 | 0.89 | KCNA3 (0.82) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3895307 | 0.89 | KCNA3 (0.82) | KCNA3MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143965-B1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2009-02-25 | — | — | EP | claimed |
| EP-1368020-B1 | METHOD FOR IDENTIFYING MAXI-K CHANNEL BLOCKERS | MERCK & CO INC (US) | 2008-03-05 | — | — | EP | claimed |