Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.68 |
| ▸ | PTPN2 | P17706 | 8/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3903444 | 0.99 | PTPN1 (0.67) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3908135 | 0.93 | PTPN1 (0.73) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3909247 | 0.92 | PTPN1 (0.67) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL13867966 | 0.91 | PTPN1 (0.55) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3909033 | 0.90 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3909235 | 0.89 | PTPN1 (0.69) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3905200 | 0.89 | PTPN1 (0.85) | PTPN1PTPN2PTPRCCYP2C9 | |
| Hydrochloric Acid SCHEMBL3906442 | 0.89 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3908821 | 0.89 | PTPN1 (0.54) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3908037 | 0.88 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | disclosed |
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | disclosed |
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | disclosed |
| EP-1202728-B1 | PEROXOVANADIUM COMPOUNDS AS PROTEIN TYROSINE PHOSPHATASE (PTP) INHIBITORS: THEIR INHIBITORY EFFECTS ON ANGIOGENESIS, RESTENOSIS AND THE PRODUCTION OF ENDOTHELINS. | UNIV LAVAL (CA) | 2005-10-19 | — | — | EP | disclosed |
| US-20050203087-A1 | Inhibitors of protein tyrosine phosphatase 1B | WYETH | 2005-09-15 | — | — | US | disclosed |
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |
| EP-1511493-A1 | USE OF PEROXOVANADIUM COMPOUNDS AS TUMOUR CELL GROWTH SUPPRESSOR | UNIVERSITE LAVAL (CA) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003097068-A1 | USE OF PEROXOVANADIUM COMPOUNDS AS TUMOUR CELL GROWTH SUPPRESSOR | UNIVERSITE LAVAL (CA) | 2003-11-27 | — | — | WO | disclosed |
| US-20030055106-A1 | Therapeutic uses of peroxometallic compounds | MCGILL UNIVERSITY (CA) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203087-A1 | Inhibitors of protein tyrosine phosphatase 1B | PTPRO, PTPRS, PTPRM | PTPN1 11/4885PTPN2 17/4885PTPRC 5/4885 |
| US-20030055106-A1 | Therapeutic uses of peroxometallic compounds | PTPRO, PTPRJ, PTPRE | PTPN1 57/4885PTPN2 103/4885PTPRC 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.