SCHEMBL39050

SCHEMBL39050

Nc1ncnc2[nH]ccc12

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 2/20 0.53
TTBK1 Q5TCY1 5/20 0.50
TTBK2 Q6IQ55 5/20 0.50
JAK3 P52333 5/20 0.50
TRPA1 O75762 2/20 0.49
HPGDS O60760 1/20 0.47
HTR2C P28335 1/20 0.47
RET P07949 1/20 0.47
PI4KA P42356 1/20 0.47
XDH P47989 1/20 0.47
LRRK2 Q5S007 1/20 0.47
PI4K2B Q8TCG2 1/20 0.47
PI4K2A Q9BTU6 1/20 0.47
PI4KB Q9UBF8 1/20 0.47
PRKCI P41743 2/20 0.45
AXL P30530 1/20 0.45
JAK1 P23458 1/20 0.45
CDC7 O00311 1/20 0.45
DBF4 Q9UBU7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28332112 0.98 JAK2 (0.52) JAK2TTBK1TTBK2JAK3TRPA1
Hydrochloric Acid SCHEMBL7018150 0.98 JAK2 (0.52) JAK2TTBK1TTBK2JAK3TRPA1
Hydrochloric Acid SCHEMBL21683016 0.96 JAK2 (0.50) JAK2TTBK1TTBK2JAK3TRPA1
Hydrochloric Acid SCHEMBL17781755 0.94 JAK2 (0.49) JAK2TTBK1TTBK2JAK3TRPA1
Sulfuric Acid SCHEMBL14736382 0.89 IKBKB (0.49) JAK2TTBK1TTBK2JAK3TRPA1
Trifluoroacetic Acid SCHEMBL28330499 0.83 NOTUM (0.48) JAK2TTBK1TTBK2JAK3TRPA1
SCHEMBL1085771 0.76 PRKCI (0.53) JAK2TTBK1TTBK2JAK3TRPA1
SCHEMBL95556 0.76 TTBK1 (0.54) JAK2TTBK1TTBK2JAK3TRPA1
SCHEMBL2678646 0.76 JAK2 (0.52) JAK2TTBK1TTBK2JAK3TRPA1
SCHEMBL12997948 0.76 JAK2 (0.52) JAK2TTBK1TTBK2JAK3TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20200 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-12630827-B2 Antisense oligonucleotides targeting SCN2A for the treatment of SCN1A encephalopathies ROGCON, INC. (US) 2026-05-19 US claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-12612409-B2 Pyrrolopyrimidines as CFTR potentiators CYSTIC FIBROSIS FOUNDATION (US) 2026-04-28 US claimed
EP-4234566-B1 MODIFIED NUCLEOSIDE OR NUCLEOTIDE BGI SHENZHEN (CN) 2026-04-15 EP claimed
US-12467080-B2 PNA oligomer, use thereof for detecting DNA methylation, and method for detecting DNA methylation using same SEASUNBIO MATERIALS (KR) 2025-11-11 US claimed
US-20250320496-A1 MODULATION OF ABCB11 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-10-16 US claimed
EP-4630009-A1 ANTISENSE RNA (ASRNA) TECHNOLOGY AND USE THEREOF 1Globe Health Institute LLC (US) 2025-10-15 EP claimed
WO-1991018914-A1 SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES VICAL, INC. (US) 1991-12-12 WO claimed
EP-0431523-A2 Modified nucleotide compounds ENZO BIOCHEM, INC. (US) 1991-06-12 EP claimed
EP-0418309-A1 OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR BENNER, Steven Albert (CH) 1991-03-27 EP claimed
US-4963662-A Fluorinated nucleosides and method for treating retrovirus infections therewith AKADEMIE DER WISSENSCHAFTEN DER DDR (DD) 1990-10-16 US claimed
EP-0254268-B1 FLUORINATED NUCLEOSIDES,THEIR PREPARATION AND THEIR PHARMACEUTICAL USE AGAINST AIDS THE WELLCOME FOUNDATION LIMITED (GB) 1990-09-19 EP claimed
WO-1989012060-A1 OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR BENNER STEVEN ALBERT (CH) 1989-12-14 WO claimed
EP-0290583-A1 -g(a) OLIGONUCLEOTIDES. CENTRE NAT RECH SCIENT (FR) 1988-11-17 EP claimed
WO-1988004301-A1 alpha OLIGONUCLEOTIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) 1988-06-16 WO claimed
EP-0252683-A2 Process and reagents for DNA sequence analysis E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-13 EP claimed
US-4266048-A Synthesis of analogs of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1981-05-05 US claimed