Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.77 |
| ▸ | F2 | P00734 | 3/20 | 0.77 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902149 | 0.90 | F10 (0.62) | F10F2KLKB1 | |
| Trifluoroacetic Acid SCHEMBL3905673 | 0.88 | F10 (0.92) | F10F2PRSS1MLYCD | |
| SCHEMBL13901249 | 0.87 | F10 (1.00) | F10F2PRSS1HPGDHSD17B10 | |
| SCHEMBL3899625 | 0.84 | F10 (0.62) | F10F2PRSS1 | |
| SCHEMBL6771710 | 0.82 | F10 (0.52) | F10F2PRSS1MLYCDKLKB1 | |
| Trifluoroacetic Acid SCHEMBL3902136 | 0.78 | F10 (0.74) | F10F2 | |
| SCHEMBL4687024 | 0.78 | F10 (0.54) | F10F2HPGDHSD17B10 | |
| SCHEMBL3912337 | 0.78 | F10 (0.63) | F10F2PRSS1MLYCD | |
| SCHEMBL4685847 | 0.77 | F10 (0.53) | F10F2PRSS1KLKB1 | |
| SCHEMBL14132218 | 0.77 | F10 (0.80) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |