Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.73 |
| ▸ | PTPN2 | P17706 | 8/20 | 0.63 |
| ▸ | PTPRC | P08575 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3911662 | 0.91 | PTPN1 (0.81) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3911831 | 0.91 | PTPN1 (0.81) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3904693 | 0.91 | PTPN1 (0.81) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3906267 | 0.85 | PTPN1 (1.00) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3910558 | 0.84 | PTPN1 (1.00) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3908697 | 0.84 | PTPN1 (1.00) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3908283 | 0.84 | PTPN1 (0.85) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3906539 | 0.83 | PTPN1 (0.67) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3907296 | 0.83 | PTPN1 (0.84) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3906786 | 0.82 | PTPN1 (0.81) | PTPN1PTPN2PTPRCCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | claimed |