⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390851 | 0.96 | — | — | |
| Bromide SCHEMBL2228320 | 0.93 | — | — | |
| SCHEMBL9972347 | 0.89 | — | — | |
| SCHEMBL11413582 | 0.81 | — | — | |
| SCHEMBL11712553 | 0.73 | HRH3 (0.55) | — | |
| SCHEMBL19173238 | 0.73 | HRH3 (0.55) | — | |
| SCHEMBL8023825 | 0.73 | — | — | |
| SCHEMBL9966933 | 0.73 | HRH3 (0.55) | — | |
| SCHEMBL12811 | 0.73 | — | — | |
| SCHEMBL15462867 | 0.73 | HRH3 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756748-A | Synthesis method of mepiquat chloride | 中棉小康生物科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-109687003-A | A kind of cross-linking type alkaline anionic membrane and preparation method thereof based on piperidines | 大连理工大学 | 2019-04-26 | — | — | CN | claimed |
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | claimed |
| EP-0333427-B1 | Heterocyclic derivatives | SMITHKLINE BEECHAM FARMA (IT) | 1995-08-23 | — | — | EP | claimed |
| EP-0333427-A1 | Heterocyclic derivatives | Smithkline Beecham Farmaceutici S.p.A. (IT) | 1989-09-20 | — | — | EP | claimed |
| CN-117756748-A | Synthesis method of mepiquat chloride | 中棉小康生物科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-111825740-B | Steroid sapogenin derivative and preparation method and application thereof | 华东理工大学 | 2023-05-26 | — | — | CN | disclosed |
| EP-3131897-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-06-15 | — | — | EP | disclosed |
| CN-111825740-A | Steroid sapogenin derivative and preparation method and application thereof | 华东理工大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-110041246-A | The synthesis and application of novel Kessazulen sesquiterpene alkaloids | 中国海洋大学 | 2019-07-23 | — | — | CN | disclosed |
| CN-109687003-A | A kind of cross-linking type alkaline anionic membrane and preparation method thereof based on piperidines | 大连理工大学 | 2019-04-26 | — | — | CN | disclosed |
| EP-3131896-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2019-01-30 | — | — | EP | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |
| EP-0333427-A1 | Heterocyclic derivatives | Smithkline Beecham Farmaceutici S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |
| CN-85101921-A | Improving one's methods of preparation 7-halogen-7-deoxy-lincomycin and similar compound thereof | — | 1987-01-10 | — | — | CN | disclosed |
| EP-0103500-A2 | Phenethyl-1-alpha-phenyl-piperidine-3-propane-nitrile derivatives, their preparation and therapeutical use | SYNTHELABO (FR) | 1984-03-21 | — | — | EP | disclosed |
| US-4394312-A | Process for preparing rifamycin derivatives | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1983-07-19 | — | — | US | disclosed |
| US-4061632-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4000277-A | 3,11-Dihydro- 6H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[4,3-d]pyrimidin-6-one and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1976-12-28 | — | — | US | disclosed |
| US-3968121-A | 1,2-Diphenyl-4,5,6,7-tetrahydroindoles | STERLING DRUG INC. (US) | 1976-07-06 | — | — | US | disclosed |