Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899327 | 0.90 | EGFR (0.82) | EGFRERBB2 | |
| SCHEMBL5922891 | 0.89 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL5922718 | 0.88 | EGFR (0.82) | EGFRERBB2 | |
| SCHEMBL3901034 | 0.88 | EGFR (0.76) | EGFRERBB2 | |
| SCHEMBL5922704 | 0.88 | EGFR (0.76) | EGFRERBB2 | |
| SCHEMBL5922788 | 0.86 | EGFR (0.70) | EGFRERBB2 | |
| SCHEMBL5922629 | 0.86 | EGFR (0.83) | EGFRERBB2 | |
| SCHEMBL3964814 | 0.86 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL3897471 | 0.86 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL5922692 | 0.86 | EGFR (1.00) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654251-A4 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2009-03-11 | — | — | EP | disclosed |
| EP-1654251-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016914-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |