Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28241919 | 0.85 | MAPT (0.48) | KMT2AMEN1POLBNPC1ALDH1A1 | |
| SCHEMBL5167275 | 0.80 | NPSR1 (0.46) | TSHRTP53KMT2AMEN1POLB | |
| SCHEMBL976776 | 0.78 | TSHR (0.55) | TSHRALOX15TP53KMT2AMEN1 | |
| SCHEMBL3130237 | 0.78 | NPC1 (0.50) | TSHRALOX15TP53KMT2AMEN1 | |
| SCHEMBL8953838 | 0.77 | POLB (0.53) | TSHRALOX15TP53KMT2AMEN1 | |
| SCHEMBL4873905 | 0.75 | TSHR (0.50) | TSHRALOX15TP53KMT2AMEN1 | |
| SCHEMBL11517667 | 0.75 | TSHR (0.50) | TSHRALOX15TP53KMT2AMEN1 | |
| Terephthalic Acid SCHEMBL2187152 | 0.75 | TSHR (0.63) | TSHRALOX15TP53KMT2AMEN1 | |
| Terephthalic Acid SCHEMBL3045633 | 0.74 | TSHR (0.80) | TSHRALOX15TP53SRD5A2ALDH1A1 | |
| Terephthalic Acid SCHEMBL8209798 | 0.74 | TSHR (0.80) | TSHRALOX15TP53POLBSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921515-B2 | Methods and compositions of preparation for proteome analysis | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130172539-A1 | METHODS AND COMPOSITIONS OF PREPARATION FOR PROTEOME ANALYSIS | CASE WESTERN RESERVE UNIVERSITY (US) | 2013-07-04 | — | — | US | disclosed |
| EP-1686188-B1 | Thin membrane for measuring protease activity | FUJIFILM CORP (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1270736-B1 | FILMS FOR ASSAYING PROTEASE ACTIVITY | FUJIFILM CORP (JP) | 2009-03-11 | — | — | EP | disclosed |
| EP-1686188-A1 | Thin membrane for measuring protease activity | Fuji Photo Film Co. Ltd. (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-7067272-B2 | Thin membrane for measuring protease activity | FUJI PHOTO FILM CO., LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| US-20030148399-A1 | Film for assaying protease activity | FUJIFILM CORPORATION (JP) | 2003-08-07 | — | — | US | disclosed |
| EP-1270736-A1 | FILMS FOR ASSAYING PROTEASE ACTIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-4536346-A | TREATMENT OF ATHEROSCLEROSIS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0124791-A1 | Aralkanamidophenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1984-11-14 | — | — | EP | disclosed |