SCHEMBL39113

SCHEMBL39113

O=C(On1nnc2ccccc21)On1nnc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 4/20 0.61
HDAC3 O15379 3/20 0.60
HDAC4 P56524 3/20 0.60
HDAC1 Q13547 3/20 0.60
HDAC7 Q8WUI4 3/20 0.60
HDAC2 Q92769 3/20 0.60
HDAC10 Q969S8 3/20 0.60
HDAC11 Q96DB2 3/20 0.60
HDAC8 Q9BY41 3/20 0.60
HDAC6 Q9UBN7 3/20 0.60
HDAC9 Q9UKV0 3/20 0.60
HDAC5 Q9UQL6 3/20 0.60
TSHR P16473 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
ATM Q13315 1/20 0.50
SIRT1 Q96EB6 1/20 0.49
SIRT3 Q9NTG7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29773981 1.00 SIRT2 (0.61) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL4757056 0.90 HDAC3 (0.62) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL22927455 0.90 SIRT2 (0.56) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL20445438 0.90 SIRT2 (0.56) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL1562975 0.89 SIRT2 (0.61) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL14123347 0.89 SIRT2 (0.55) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL4600108 0.88 SIRT2 (0.51) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL239516 0.87 SIRT2 (0.60) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL30140830 0.87 SIRT2 (0.60) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL26598951 0.87 SIRT2 (0.60) SIRT2HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4120 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692166-A1 METHOD FOR PRODUCING ACTIVATED POLYETHYLENE GLYCOL DERIVATIVE NOF Corporation (JP) 2026-02-11 EP claimed
US-20260000600-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING PEGYLATED BILIRUBIN BILIX CO LTD (KR) 2026-01-01 US claimed
EP-4552640-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING PEGYLATED BILIRUBIN Bilix Co., Ltd. (KR) 2025-05-14 EP claimed
CN-119403553-A Pharmaceutical composition for preventing or treating inflammatory diseases comprising pegylated bilirubin 株式会社毕丽斯 2025-02-07 CN claimed
WO-2024203596-A1 METHOD FOR PRODUCING ACTIVATED POLYETHYLENE GLYCOL DERIVATIVE 日油株式会社 2024-10-03 WO claimed
CN-112839979-B Method for preparing releasable polymeric reagents 尼克塔治疗公司 2024-06-21 CN claimed
US-11952461-B2 Siloxy polyethylene glycol and derivatives thereof SUNBIO, INC. (KR) 2024-04-09 US claimed
CN-117779125-A Electroplating liquid medicine applied to large-aperture blind holes and process thereof 永星化工(上海)有限公司 2024-03-29 CN claimed
US-11932726-B2 Method of making releasable polymeric reagents NEKTAR THERAPEUTICS (US) 2024-03-19 US claimed
WO-2024010353-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING PEGYLATED BILIRUBIN 주식회사 빌릭스 2024-01-11 WO claimed
US-5981709-A CONJUGATING AN ACID STABLE ALPHA-INTERFERON WITH AN ACTIVATED NON-ANTIGENIC POLYMER IN SOLUTION, ACIDIFYING SOLUTION TO SELECTIVELY CLEAVE LINKAGES THAT REDUCE BIOACTIVITY, ADJUST SOLUTION TO A PHYSIOLOGICAL PH ENZON, INC. (US) 1999-11-09 US claimed
WO-1999055377-A2 POLYOL-IFN-BETA CONJUGATES APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 1999-11-04 WO claimed
WO-1999032140-A1 ALPHA-INTERFERON-POLYMER-CONJUGATES HAVING ENHANCED BIOLOGICAL ACTIVITY AND METHODS OF PREPARING THE SAME ENZON, INC. (US) 1999-07-01 WO claimed
US-5753389-A Organic carbonate additives for nonaqueous electrolyte in alkali metal electrochemical cells WILSON GREATBATCH LTD. (US) 1998-05-19 US claimed
EP-0803924-A2 Organic carbonate additives for nonaqueous electrolyte in alkali metal electrochemical cells WILSON GREATBATCH LTD. (US) 1997-10-29 EP claimed
US-5446134-A Reacting bis(fluorosulfonyl)methane salt with cyanogen halide or pseudohalide CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1995-08-29 US claimed
US-5147961-A PREPARATION OF HYDROXYPOLYAMIDES SIEMENS AKTIENGESELLSCHAFT (DE) 1992-09-15 US claimed
US-5096999-A CATALYTIC PREPARATION OF HYDROXYPOLYAMIDES SIEMENS AKTIENGESELLSCHAFT (DE) 1992-03-17 US claimed
EP-0391196-A2 Production of hydroxypolyamides SIEMENS AKTIENGESELLSCHAFT (DE) 1990-10-10 EP claimed
EP-0370382-A2 Urea dipeptide derivatives with a renin-inhibiting activity, process to produce them, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed