⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659736 | 0.68 | — | — | |
| SCHEMBL4953700 | 0.68 | — | — | |
| SCHEMBL179883 | 0.67 | — | — | |
| SCHEMBL15264169 | 0.67 | — | — | |
| SCHEMBL3679210 | 0.65 | — | — | |
| SCHEMBL3759334 | 0.64 | — | — | |
| SCHEMBL17390952 | 0.64 | — | — | |
| SCHEMBL14720843 | 0.64 | — | — | |
| SCHEMBL11824482 | 0.64 | — | — | |
| SCHEMBL2382240 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 512 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036319-B2 | Polyvalent sting activating compositions and uses thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-07-16 | — | — | US | disclosed |
| WO-2024112397-A1 | COMBINATION THERAPIES COMPRISING KRAS INHIBITORS AND SPH2 INHIBITORS | HUYABIO INTERNATIONAL, LLC (US) | 2024-05-30 | — | — | WO | disclosed |
| US-20240141084-A1 | BIOFOULING RESISTANT COATINGS AND METHODS OF MAKING AND USING THE SAME | SILQ TECHNOLOGIES CORPORATION | 2024-05-02 | — | — | US | disclosed |
| US-11970731-B2 | Enhancement of nucleic acid polymerization by aromatic compounds | Roche Sequencing Solutions, Inc. (US) | 2024-04-30 | — | — | US | disclosed |
| US-11964971-B2 | Methods and compositions for modulating splicing | SKYHAWK THERAPEUTICS, INC. (US) | 2024-04-23 | — | — | US | disclosed |
| EP-4333850-A1 | SHP2 INHIBITOR MONOTHERAPY AND USES THEREOF | Huyabio International, LLC (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-4334318-A1 | COMBINATION THERAPIES COMPRISING SHP2 INHIBITORS AND PD-1 INHIBITORS | Huyabio International, LLC (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-4334317-A1 | COMBINATION THERAPIES COMPRISING SHP2 INHIBITORS AND EGFR TYROSINE KINASE INHIBITORS | Huyabio International, LLC (US) | 2024-03-13 | — | — | EP | disclosed |
| CN-117677619-A | Combination therapy comprising an SHP2 inhibitor and a PD-1 inhibitor | 沪亚生物国际有限责任公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-3568390-B1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) | 2024-03-06 | — | — | EP | disclosed |
| US-5753635-A | Purine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1998015547-A1 | THIO ACID DERIVED MONOCYCLIC N-HETEROCYCLICS AS ANTICOAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |
| WO-1998011094-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-03-19 | — | — | WO | disclosed |
| WO-1998007723-A1 | BICYCLIC PYRIMIDINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |
| WO-1998007725-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |
| EP-0813525-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5693641-A | ENZYME INHIBITOR TREATING BLOOD DISORDER | BERLEX LABORATORIES INC. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5691364-A | Benzamidine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| WO-1997029067-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (DE) | 1997-08-14 | — | — | WO | disclosed |
| WO-1996028427-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-09-19 | — | — | WO | disclosed |