Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.79 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinimide SCHEMBL28744286 | 0.96 | CRBN (0.85) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL7263756 | 0.96 | — | — | |
| Succinimide SCHEMBL1002212 | 0.93 | — | — | |
| Succinimide SCHEMBL22806340 | 0.89 | — | — | |
| Succinimide SCHEMBL1326078 | 0.89 | CRBN (1.00) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL8361206 | 0.89 | CRBN (1.00) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL1600526 | 0.89 | — | — | |
| Succinimide SCHEMBL1466558 | 0.89 | — | — | |
| Succinimide SCHEMBL774 | 0.89 | — | — | |
| Succinimide SCHEMBL15169635 | 0.85 | CRBN (0.92) | CRBNNPC1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2023941-B1 | PROTEIN CROSSLINKERS, CROSSLINKING METHODS AND APPLICATIONS THEREOF | INCEPT LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| US-9498557-B2 | Crosslinking methods and applications thereof | INCEPT, LLC (US) | 2016-11-22 | — | — | US | disclosed |
| US-20090311338-A1 | CROSSLINKING METHODS AND APPLICATIONS THEREOF | INCEPT LLC | 2009-12-17 | — | — | US | disclosed |
| US-7597882-B2 | Protein crosslinkers, crosslinking methods and applications thereof | INCEPT LLC (US) | 2009-10-06 | — | — | US | disclosed |
| EP-2023941-A2 | PROTEIN CROSSLINKERS, CROSSLINKING METHODS AND APPLICATIONS THEREOF | Incept, LLC (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007127198-A2 | PROTEIN CROSSLINKERS, CROSSLINKING METHODS AND APPLICATIONS THEREOF | INCEPT, LLC (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20070248567-A1 | Protein crosslinkers, crosslinking methods and applications thereof | AUGMENIX, INC. | 2007-10-25 | — | — | US | disclosed |
| US-4206061-A | OIL AND GRAPHITIC CARBON | THE BRITISH PETROLEUM COMPANY LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |