Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14303490 | 1.00 | KCNH2 (1.00) | KCNH2HRH3 | |
| SCHEMBL14310561 | 1.00 | KCNH2 (1.00) | KCNH2HRH3 | |
| SCHEMBL3356256 | 0.88 | KCNH2 (0.78) | KCNH2HRH3 | |
| SCHEMBL14310577 | 0.88 | KCNH2 (0.78) | KCNH2HRH3 | |
| SCHEMBL14302700 | 0.88 | HRH3 (0.78) | KCNH2HRH3 | |
| SCHEMBL3326712 | 0.88 | HRH3 (0.78) | KCNH2HRH3 | |
| SCHEMBL14303871 | 0.86 | KCNH2 (0.75) | KCNH2HRH3 | |
| SCHEMBL3325617 | 0.86 | KCNH2 (0.75) | KCNH2HRH3 | |
| SCHEMBL3320691 | 0.84 | KCNH2 (0.79) | KCNH2HRH3 | |
| SCHEMBL14303494 | 0.84 | KCNH2 (0.79) | KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035372-A1 | MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-03-18 | — | — | EP | claimed |
| WO-2008005338-A1 | MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2008-01-10 | — | — | WO | claimed |