SCHEMBL3915985

SCHEMBL3915985

FC(F)(F)C(F)(OC(F)(C(F)(F)F)C(F)(F)Cc1ccccc1)C(F)(F)Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
LMNA P02545 1/20 0.36
CYP2D6 P10635 1/20 0.36
TSHR P16473 3/20 0.36
CES1 P23141 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
FDPS P14324 1/20 0.34
PTPN1 P18031 1/20 0.34
CALM1 P0DP23 1/20 0.33
NR3C1 P04150 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
TRPA1 O75762 1/20 0.32
EPHX2 P34913 1/20 0.32
CES2 O00748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3277336 0.80 SLC6A2 (0.46) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL18588695 0.76 SLC6A2 (0.43) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL3915983 0.76 SLC6A2 (0.43) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL31247980 0.75 SLC6A2 (0.46) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL17943302 0.71 SLC6A2 (0.54) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL29299420 0.71 SLC6A2 (0.43) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL28510143 0.70 SLC6A2 (0.46) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL11021341 0.70 SLC6A2 (0.46) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL3248504 0.70 SLC6A2 (0.46) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL17940749 0.70 CYP1A2 (0.50) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7322694-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2008-01-29 US claimed
EP-1714182-A2 HYBRID CONTACT LENS SYSTEM AND METHOD Quarter Lambda Technologies Inc. (US) 2006-10-25 EP claimed
WO-2005079290-A2 HYBRID CONTACT LENS SYSTEM AND METHOD SYNERGEYES, INC. (US) 2005-09-01 WO claimed
US-20050018130-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2005-01-27 US claimed
US-7585074-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2009-09-08 US disclosed
US-7401922-B2 Method and apparatus for reducing or eliminating the progression of myopia SYNERGEYES, INC. (US) 2008-07-22 US disclosed
US-7322694-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2008-01-29 US disclosed
US-20070013869-A1 HYBRID CONTACT LENS SYSTEM AND METHOD DAHI ALI 2007-01-18 US disclosed
US-7163292-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2007-01-16 US disclosed
US-20060285072-A1 Hybrid contact lens system and method DAHI ALI 2006-12-21 US disclosed
US-20060256284-A1 Hybrid contact lens system and method DAHI ALI 2006-11-16 US disclosed
WO-2006113149-A2 METHOD AND APPARATUS FOR REDUCING OR ELIMINATING THE PROGRESSION OF MYOPIA SYNERGEYES, INC. (US) 2006-10-26 WO disclosed
US-20060238713-A1 HYBRID CONTACT LENS SYSTEM AND METHOD QUARTER LAMBDA TECHNOLOGIES INC. 2006-10-26 US disclosed
EP-1714182-A2 HYBRID CONTACT LENS SYSTEM AND METHOD Quarter Lambda Technologies Inc. (US) 2006-10-25 EP disclosed
US-20060232743-A1 Method and apparatus for reducing or eliminating the progression of myopia SYNERGEYES, INC. 2006-10-19 US disclosed
US-7104648-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2006-09-12 US disclosed
WO-2005079290-A2 HYBRID CONTACT LENS SYSTEM AND METHOD SYNERGEYES, INC. (US) 2005-09-01 WO disclosed
US-20050018130-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2005-01-27 US disclosed
US-20040212779-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2004-10-28 US disclosed
US-20040179167-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2004-09-16 US disclosed