Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 10/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | RHOC | P08134 | 1/20 | 0.38 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3912792 | 0.86 | MIF (0.39) | RAB9ANPC1SMN1; SMN2MIFHDAC6 | |
| SCHEMBL3912693 | 0.85 | SMN1; SMN2 (0.44) | RAB9ANPC1SMN1; SMN2MIFHDAC6 | |
| SCHEMBL1002341 | 0.85 | F10 (0.54) | F10F2 | |
| SCHEMBL3990603 | 0.77 | F10 (0.43) | RAB9ANPC1SMN1; SMN2F10MIF | |
| SCHEMBL1004839 | 0.73 | F10 (0.44) | RAB9ANPC1SMN1; SMN2F10MIF | |
| SCHEMBL1096632 | 0.72 | F10 (0.43) | F10MIFMEN1KMT2A | |
| SCHEMBL1096553 | 0.72 | F10 (0.47) | F10MEN1KMT2A | |
| SCHEMBL3233576 | 0.71 | F10 (0.38) | RAB9ANPC1SMN1; SMN2F10F2 | |
| SCHEMBL1096474 | 0.71 | NPC1 (0.52) | RAB9ANPC1F10MEN1CYP1A2 | |
| SCHEMBL1096261 | 0.70 | F10 (0.50) | F10F2MEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032567-A1 | SUBSTITUTED HETEROCYCLES AND USE THEREOF | Bayer HealthCare AG (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007137792-A1 | SUBSTITUTED HETEROCYCLES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |