Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.65 |
| ▸ | FAP | Q12884 | 10/20 | 0.57 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.53 |
| ▸ | GHSR | Q92847 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919837 | 0.89 | DPP4 (0.70) | DPP4FAPPOU2F2ADORA3CHRM1 | |
| SCHEMBL29350672 | 0.89 | DPP4 (0.70) | DPP4FAPPOU2F2ADORA3CHRM1 | |
| SCHEMBL16794574 | 0.86 | DPP4 (0.55) | DPP4FAPPOU2F2ADORA3CHRM1 | |
| SCHEMBL3917495 | 0.83 | DPP4 (0.82) | DPP4FAPPOU2F2ADORA3CHRM1 | |
| SCHEMBL8273215 | 0.83 | DPP4 (0.61) | DPP4FAPPOU2F2ADORA3CHRM1 | |
| SCHEMBL3918551 | 0.83 | DPP4 (0.51) | DPP4FAPPOU2F2ADORA3CHRM1 | |
| SCHEMBL637987 | 0.80 | DPP4 (0.64) | DPP4FAPPOU2F2ADORA3CHRM1 | |
| SCHEMBL637704 | 0.80 | DPP4 (1.00) | DPP4FAPPOU2F2ADORA3CHRM1 | |
| SCHEMBL637705 | 0.80 | DPP4 (1.00) | DPP4FAPPOU2F2ADORA3CHRM1 | |
| SCHEMBL639200 | 0.80 | DPP4 (1.00) | DPP4FAPPOU2F2ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550455-B2 | 8-(piperazin-1yl)- and 8-([1,4]diazepan-1yl)-xanthines, the preparation thereof and their use as pharmaceutical composition | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-23 | — | — | US | disclosed |
| US-20050130985-A1 | 8-(piperazin-1yl)- and 8-([1,4]diazepan-1yl)-xanthines, the preparation thereof and their use as pharmaceutical composition | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130985-A1 | 8-(piperazin-1yl)- and 8-([1,4]diazepan-1yl)-xanthines, the preparation thereof and their use as pharmaceutical composition | DPP8, DPP4, DPP7 | DPP4 2/4885FAP 22/4885POU2F2 1980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.