SCHEMBL3919940

SCHEMBL3919940

CC(C)(C)c1cc(CCC(=O)NCCO)cc(C(C)(C)C)c1O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.79
KMT2A Q03164 4/20 0.79
MEN1 O00255 3/20 0.62
GSR P00390 2/20 0.55
MAOB P27338 3/20 0.55
MAOA P21397 2/20 0.55
ACHE P22303 1/20 0.55
ALDH1A1 P00352 3/20 0.49
HTT P42858 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 2/20 0.49
AGTR1 P30556 1/20 0.49
PCNA P12004 1/20 0.48
MAPK1 P28482 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
GSK3B P49841 2/20 0.44
GMNN O75496 1/20 0.44
GABBR2 O75899 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1149914 0.92 GAA (0.86) GAAKMT2AMEN1GSRMAOB
SCHEMBL7941169 0.92 GAA (0.67) GAAKMT2AMEN1GSRMAOB
SCHEMBL7944730 0.92 GAA (0.75) GAAKMT2AMEN1GSRMAOB
SCHEMBL4569533 0.91 GAA (0.83) GAAKMT2AMEN1GSRMAOB
SCHEMBL7941028 0.90 GAA (0.73) GAAKMT2AMEN1GSRMAOB
SCHEMBL1149604 0.90 GAA (0.81) GAAKMT2AMEN1MAOBMAOA
SCHEMBL76483 0.90 GAA (0.81) GAAKMT2AMEN1GSRMAOB
SCHEMBL7943176 0.89 GAA (0.71) GAAKMT2AMEN1GSRMAOB
SCHEMBL11667488 0.88 GAA (0.79) GAAKMT2AMEN1MAOBMAOA
SCHEMBL11609517 0.88 GAA (0.79) GAAKMT2AMEN1GSRMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7497935-B2 Electrodepositable coating compositions and methods related thereto PPG INDUSTRIES OHIO, INC. (US) 2009-03-03 US disclosed
EP-1781742-A1 ELECTRODEPOSITABLE COATING COMPOSITIONS AND METHODS RELATED THERETO PPG Industries Ohio, Inc. (US) 2007-05-09 EP disclosed
WO-2006026448-A1 ELECTRODEPOSITABLE COATING COMPOSITIONS AND METHODS RELATED THERETO PPG INDUSTRIES OHIO, INC. (US) 2006-03-09 WO disclosed
US-20060042949-A1 Electrodepositable coating compositions and methods related thereto PPG INDUSTRIES OHIO INC. 2006-03-02 US disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-6075159-A USE AS A STABILIZER FOR AN ORGANIC MATERIAL SUCH AS THERMOPLASTIC RESINS, THERMOSETTING RESINS, NATURAL OR SYNTHETIC RUBBERS, MINERAL OILS, LUBRICATING OILS, ADHESIVES AND PAINTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-06-13 US disclosed
US-5962683-A STABILIZING ORGANIC MATERIAL AGAINST THE DAMAGING EFFECT OF LIGHT, OXYGEN AND/OR HEAT. CIBA SPECIALTY CHEMICALS CORP. (US) 1999-10-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
EP-0816346-A1 Oxazoline compounds as stabilizers Ciba SC Holding AG (CH) 1998-01-07 EP disclosed
US-4704470-A INCORPORATION IN ADDITION POLYMER THE DOW CHEMICAL COMPANY (US) 1987-11-03 US disclosed
EP-0009866-B1 PHENOLIC ESTERAMIDE ANTIOXIDANTS AND THEIR USE UNIROYAL, INC. (US) 1982-08-04 EP disclosed
US-4305868-A Phenolic esteramide antioxidants UNIROYAL, INC. (US) 1981-12-15 US disclosed
EP-0009866-A1 Phenolic esteramide antioxidants and their use UNIROYAL, INC. (US) 1980-04-16 EP disclosed