SCHEMBL3920243

SCHEMBL3920243

N#CC(C#N)=C1c2cnccc2-c2ccc([N+](=O)[O-])cc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.60
EGFR P00533 1/20 0.51
MAPT P10636 7/20 0.49
KDM4E B2RXH2 3/20 0.49
MAPK1 P28482 2/20 0.49
TDP1 Q9NUW8 2/20 0.47
PTPRC P08575 3/20 0.43
S100A4 P26447 2/20 0.43
PKM P14618 2/20 0.43
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MCL1 Q07820 1/20 0.39
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10943739 0.87 HPRT1 (0.74) HPRT1EGFRMAPTKDM4EMAPK1
SCHEMBL11586212 0.84 HPRT1 (0.70) HPRT1EGFRMAPTKDM4EMAPK1
SCHEMBL11573692 0.83 HPRT1 (0.42) HPRT1EGFRMAPTKDM4EMAPK1
SCHEMBL11695991 0.82 HPRT1 (0.67) HPRT1EGFRMAPTKDM4EMAPK1
SCHEMBL11588993 0.81 HPRT1 (0.69) HPRT1EGFRMAPTKDM4EMAPK1
SCHEMBL11589459 0.79 HPRT1 (0.63) HPRT1EGFRMAPTKDM4EMAPK1
SCHEMBL29413354 0.75 HPRT1 (1.00) HPRT1EGFRMAPTKDM4EMAPK1
SCHEMBL1034255 0.75 HPRT1 (1.00) HPRT1EGFRMAPTKDM4EMAPK1
SCHEMBL30309848 0.75 HPRT1 (1.00) HPRT1EGFRMAPTKDM4EMAPK1
SCHEMBL11587481 0.73 HPRT1 (0.77) HPRT1EGFRMAPTKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3974167-A (7-Nitro-2-aza-9-fluorenylidene) malononitrile RICOH CO., LTD. (JA) 1976-08-10 US claimed
US-7521162-B2 Organophotoreceptor with a charge transport material having two epoxidated-carbazolyl groups SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-04-21 US disclosed
US-7501216-B2 Azine-based charge transport materials SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-03-10 US disclosed
EP-1293837-B1 Electrophotographic organophotoreceptors SAMSUNG ELECTRONICS CO LTD (KR) 2008-10-08 EP disclosed
US-7432028-B2 Polymeric charge transport compositions SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-10-07 US disclosed
EP-1482377-B1 Azine-based charge transport materials SAMSUNG ELECTRONICS CO LTD (KR) 2008-03-26 EP disclosed
US-7300732-B2 Organophotoreceptors with azine-based compounds SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-27 US disclosed
EP-1519240-B1 Organophotoreceptor with charge transport material having bis(9-fluorenone) azine groups SAMSUNG ELECTRONICS CO LTD (KR) 2007-06-20 EP disclosed
US-7189483-B2 Charge transport materials having heteroaromatic hydrazone groups SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-03-13 US disclosed
EP-1555577-B1 Organophotoreceptor with a charge transport material having two epoxidated-carbazolyl groups SAMSUNG ELECTRONICS CO LTD (KR) 2007-02-28 EP disclosed
US-4845263-A Layered photoresponsive imaging members with sulfur incorporated dicyanomethylenefluorene carboxylate compositions of matter XEROX CORPORATION (US) 1989-07-04 US disclosed
EP-0135339-B1 LAYERED PHOTORESPONSIVE DEVICES XEROX CORPORATION (US) 1988-01-07 EP disclosed
US-4609602-A Photoresponsive imaging members with electron transporting layers XEROX CORPORATION (US) 1986-09-02 US disclosed
US-4606861-A Process for obtaining anthraquinodimethane derivatives and anthrone derivatives XEROX CORPORATION (US) 1986-08-19 US disclosed
US-4559287-A ARYL AMINE AS CRYSTAL GROWTH INHIBITOR; XEROGRAPHY XEROX CORPORATION (US) 1985-12-17 US disclosed
US-4546059-A Layered photoresponsive imaging members with sulfur incorporated dicyanomethylenefluorene carboxylate compositions XEROX CORPORATION (US) 1985-10-08 US disclosed
EP-0135339-A1 Layered photoresponsive devices XEROX CORPORATION (US) 1985-03-27 EP disclosed
US-4474865-A FLUORENYLIDENE COMPOUNDS XEROX CORPORATION (US) 1984-10-02 US disclosed
US-3974167-A (7-Nitro-2-aza-9-fluorenylidene) malononitrile RICOH CO., LTD. (JA) 1976-08-10 US disclosed
US-3974167-A (7-Nitro-2-aza-9-fluorenylidene) malononitrile RICOH CO., LTD. (JA) 1976-08-10 US disclosed