Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105692 | 0.98 | HTT (0.58) | HTTMEN1APAF1RGS12HSP90AA1 | |
| SCHEMBL14454728 | 0.96 | HTT (0.55) | HTTMEN1APAF1RGS12HSP90AA1 | |
| SCHEMBL13464660 | 0.91 | HTT (0.52) | HTTMAPK1KMT2ATSHR | |
| SCHEMBL13464661 | 0.83 | KMT2A (0.48) | HTTMEN1KMT2ALMNATSHR | |
| Bromide SCHEMBL30903821 | 0.82 | HTT (0.78) | HTTMEN1KMT2ABCHEACHE | |
| SCHEMBL13556906 | 0.81 | MAPT (0.50) | HTTMEN1APAF1RGS12HSP90AA1 | |
| Azelaic Acid SCHEMBL3807504 | 0.80 | TSHR (0.60) | MEN1KMT2ALMNATSHRNFKB1 | |
| P-Xylene SCHEMBL36101 | 0.80 | TSHR (0.60) | MEN1KMT2ALMNATSHRNFKB1 | |
| Sebacic Acid SCHEMBL36102 | 0.80 | TSHR (0.60) | MEN1KMT2ALMNATSHRNFKB1 | |
| Sebacic Acid SCHEMBL28279615 | 0.80 | TSHR (0.60) | MEN1KMT2ALMNATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250186600-A1 | EXCIPIENT COMPOUNDS FOR PROTEIN FORMULATIONS | COMERA LIFE SCIENCES, INC. | 2025-06-12 | — | — | US | disclosed |
| US-20230270864-A1 | EXCIPIENT COMPOUNDS FOR PROTEIN FORMULATIONS | COMERA LIFE SCIENCES, INC. | 2023-08-31 | — | — | US | disclosed |
| EP-4210757-A2 | EXCIPIENT COMPOUNDS FOR PROTEIN FORMULATIONS | Comera Life Sciences, Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| US-20230027396-A1 | EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS | COMERA LIFE SCIENCES, INC. | 2023-01-26 | — | — | US | disclosed |
| US-20220401559-A1 | EXCIPIENT COMPOUNDS FOR PROTEIN FORMULATIONS | COMERA LIFE SCIENCES, INC. | 2022-12-22 | — | — | US | disclosed |
| WO-2022056220-A2 | EXCIPIENT COMPOUNDS FOR PROTEIN FORMULATIONS | REFORM BIOLOGICS, INC. (US) | 2022-03-17 | — | — | WO | disclosed |
| US-20220062423-A1 | EXCIPIENT COMPOUNDS FOR PROTEIN FORMULATIONS | COMERA LIFE SCIENCES, INC. | 2022-03-03 | — | — | US | disclosed |
| EP-3886909-A1 | EXCIPIENT COMPOUNDS FOR PROTEIN PROCESSING | ReForm Biologics, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| US-20210113697-A1 | EXCIPIENT COMPOUNDS FOR PROTEIN FORMULATIONS | COMERA LIFE SCIENCES, INC. | 2021-04-22 | — | — | US | disclosed |
| WO-2020112855-A1 | EXCIPIENT COMPOUNDS FOR PROTEIN PROCESSING | REFORM BIOLOGICS, LLC (US) | 2020-06-04 | — | — | WO | disclosed |
| US-7563907-B2 | Compounds based on polymethines | DYOMICS GMBH (DE) | 2009-07-21 | — | — | US | disclosed |
| US-20040260093-A1 | Compound, especially marker-dye on the basis of polymethines | DYOMICS GMBH (DE) | 2004-12-23 | — | — | US | disclosed |
| EP-1318177-B1 | Compound, in particular marker-dye, based on polymethines | DYOMICS GMBH (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-20030165942-A1 | Compound, especially marker-dye, on the basis of polymethines | DYOMICS GMBH (DE) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030165942-A1 | Compound, especially marker-dye, on the basis of polymethines | MKI67, CYBA, IK | ACHE 1739/4885HTT 2692/4885MEN1 2072/4885 |
| US-20040260093-A1 | Compound, especially marker-dye on the basis of polymethines | MKI67, IK, CYBA | ACHE 1959/4885HTT 2664/4885MEN1 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.