Bicarbonate

Bicarbonate

SCHEMBL3923085

CCCC(C)(C#N)N=NC(C)(C#N)CCC.O=C(O)O.O=C(O)O

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221492 0.89
SCHEMBL221493 0.89
Acetic Acid SCHEMBL30528137 0.87
SCHEMBL7781958 0.83
SCHEMBL11868013 0.83
SCHEMBL7781956 0.83
SCHEMBL7095031 0.83
SCHEMBL11868019 0.83
SCHEMBL7098976 0.83
SCHEMBL7787405 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948698-B1 PROCESS FOR PRODUCTION OF POLYMER POWDERS CONTAINING VINYLFORMAMIDE UNITS BASF SE (DE) 2009-03-04 EP disclosed
EP-0612772-B1 Luminiscent copolymers BAYER AG (DE) 1997-06-04 EP disclosed
EP-0612772-A1 Luminiscent copolymers BAYER AG (DE) 1994-08-31 EP disclosed
EP-0278026-B1 USE OF WATER SOLUBLE POLYMERS OF ACRYLIC OR METHACRYLIC ACID AS GRINDING AIDS FOR CALCIUM CARBONATE BASF Aktiengesellschaft (DE) 1991-05-15 EP disclosed
EP-0223063-B1 PROCESS FOR THE CONTINUOUS PREPARATION OF CROSS-LINKED GELATINOUS POLYMERS WITH A SMALL PARTICLE SIZE BASF Aktiengesellschaft (DE) 1991-05-08 EP disclosed
EP-0243768-B1 PROCESS FOR PREPARING POLYMERS IN PEARL FORM BASED ON HYDROSOLUBLE ETHYLENICALLY UNSATURATED MONOMERS BASF Aktiengesellschaft (DE) 1990-11-14 EP disclosed
EP-0243768-A2 Process for preparing polymers in pearl form based on hydrosoluble ethylenically unsaturated monomers BASF Aktiengesellschaft (DE) 1987-11-04 EP disclosed