Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.64 |
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.62 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21632208 | 0.87 | TLR8 (0.67) | TLR8TLR7NUDT1 | |
| SCHEMBL14592801 | 0.87 | TLR7 (0.56) | TLR8TLR7NUDT1 | |
| SCHEMBL18588112 | 0.87 | TLR8 (0.66) | TLR8TLR7NUDT1 | |
| SCHEMBL5807939 | 0.86 | TLR8 (0.56) | TLR8TLR7NUDT1 | |
| SCHEMBL7253813 | 0.86 | TLR8 (0.65) | TLR8TLR7NUDT1 | |
| Hydrochloric Acid SCHEMBL18588055 | 0.86 | TLR8 (0.65) | TLR8TLR7NUDT1 | |
| SCHEMBL21632302 | 0.85 | TLR7 (0.67) | TLR8TLR7NUDT1 | |
| SCHEMBL5747357 | 0.85 | TLR8 (0.64) | TLR8TLR7NUDT1 | |
| SCHEMBL23638058 | 0.84 | TLR8 (0.63) | TLR8TLR7NUDT1 | |
| SCHEMBL5750404 | 0.83 | TLR8 (0.62) | TLR8TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450804-B9 | PHARMACEUTICAL FORMULATIONS COMPRISING AN IMMUNE RESPONSE MODIFIER | 3M INNOVATIVE PROPERTIES CO (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1450804-B1 | PHARMACEUTICAL FORMULATIONS COMPRISING AN IMMUNE RESPONSE MODIFIER | 3M INNOVATIVE PROPERTIES CO (US) | 2008-08-27 | — | — | EP | disclosed |