Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | KDR | P35968 | 8/20 | 0.57 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923867 | 0.99 | HPGD (0.70) | HPGDKDRFGFR3BACE1DYRK3 | |
| SCHEMBL3925188 | 0.97 | HPGD (0.69) | HPGDKDRFGFR3BACE1DYRK3 | |
| SCHEMBL3925191 | 0.86 | HPGD (0.67) | HPGDKDRFGFR3BACE1DYRK3 | |
| SCHEMBL24329732 | 0.84 | HPGD (0.65) | HPGDKDRFGFR3BACE1DYRK3 | |
| SCHEMBL23675321 | 0.82 | HPGD (1.00) | HPGDKDRFGFR3NPC1RAB9A | |
| SCHEMBL23685645 | 0.79 | FGFR3 (0.53) | HPGDKDRFGFR3 | |
| SCHEMBL3920430 | 0.79 | HPGD (0.47) | HPGDKDRFGFR3NPC1RAB9A | |
| SCHEMBL3022584 | 0.78 | KDR (0.69) | HPGDKDRFGFR3DYRK1ARIPK2 | |
| SCHEMBL22588131 | 0.77 | HPGD (0.45) | HPGDKDRFGFR3EGLN1MAP4K4 | |
| SCHEMBL25250708 | 0.76 | EGLN2 (0.56) | HPGDKDRMAP4K4FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563797-B2 | Substituted imidazo(1,2-A)pyrimidines and imidazo(1,2-A) pyridines as cannabinoid receptor ligands | Forest Laboratories Holding Limited (BM) | 2009-07-21 | — | — | US | disclosed |
| US-20080058350-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058350-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES | CNR2, CNR1, P2RY4 | HPGD 1090/4885KDR 814/4885FGFR3 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.