Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468181 | 0.85 | KDM4E (0.37) | PTPRBRAB9ANPC1MAPTLMNA | |
| SCHEMBL23303492 | 0.82 | PTPRB (0.40) | PTPRBRAB9ANPC1MAPTLMNA | |
| SCHEMBL468179 | 0.82 | PTPRB (0.46) | PTPRBRAB9ANPC1MAPTLMNA | |
| SCHEMBL23303496 | 0.82 | PTPRB (0.40) | PTPRBRAB9ANPC1MAPTLMNA | |
| SCHEMBL500491 | 0.82 | PTPRB (0.46) | PTPRBRAB9ANPC1MAPTLMNA | |
| SCHEMBL17083263 | 0.81 | MAPT (0.41) | PTPRBRAB9ANPC1MAPTLMNA | |
| SCHEMBL683502 | 0.81 | MAPT (0.41) | PTPRBRAB9ANPC1MAPTLMNA | |
| SCHEMBL501297 | 0.81 | MAPT (0.41) | PTPRBRAB9ANPC1MAPTLMNA | |
| Bromide SCHEMBL23303501 | 0.80 | MAPT (0.40) | PTPRBRAB9ANPC1MAPTLMNA | |
| Bromide SCHEMBL500138 | 0.80 | MAPT (0.40) | PTPRBRAB9ANPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038265-A2 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | The Procter and Gamble Company (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008002570-A2 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |