Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 17/20 | 0.58 |
| ▸ | EGLN3 | Q9H6Z9 | 15/20 | 0.54 |
| ▸ | EGLN2 | Q96KS0 | 12/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422503 | 0.80 | EGLN1 (0.61) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL3420498 | 0.80 | EGLN3 (0.66) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL17629594 | 0.74 | EGLN1 (1.00) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL3419613 | 0.72 | EGLN3 (0.61) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL12913729 | 0.72 | EGLN1 (0.84) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL4738691 | 0.72 | EGLN1 (0.59) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL3423763 | 0.71 | EGLN1 (0.61) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL959932 | 0.70 | EGLN1 (0.76) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL959312 | 0.70 | EGLN1 (0.76) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL959931 | 0.70 | EGLN1 (0.76) | EGLN1EGLN3EGLN2CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2037922-A2 | PROLYL HYDROXYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2009-03-25 | — | — | EP | claimed |
| WO-2007150011-A2 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-12-27 | — | — | WO | claimed |
| EP-2037922-A2 | PROLYL HYDROXYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007150011-A2 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |