Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 11/20 | 0.44 |
| ▸ | FLT1 | P17948 | 4/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924825 | 0.93 | KDR (0.52) | KMT2AKDRFLT1TRPV1 | |
| SCHEMBL1942512 | 0.90 | KDR (0.56) | KMT2AKDR | |
| SCHEMBL1941875 | 0.89 | KMT2A (0.49) | KMT2AKDRFLT1TRPV1NAMPT | |
| SCHEMBL3932887 | 0.88 | KMT2A (0.48) | KMT2AKDRFLT1TRPV1NAMPT | |
| SCHEMBL1941150 | 0.88 | KDR (0.55) | KMT2AKDRFLT1TRPV1NAMPT | |
| SCHEMBL3932845 | 0.87 | KMT2A (0.44) | KMT2AKDR | |
| SCHEMBL1941540 | 0.86 | KMT2A (0.44) | KMT2AKDR | |
| SCHEMBL3926542 | 0.86 | KDR (0.50) | KMT2AKDRFLT1 | |
| SCHEMBL1941461 | 0.86 | KDR (0.53) | KMT2AKDRFLT1TRPV1NAMPT | |
| SCHEMBL1941840 | 0.85 | KMT2A (0.43) | KMT2AKDRFLT1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544703-B2 | Cyclic compound having 4-pyridylalkylthio group having substituted or unsubstituted amino group introduced therein | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-20070149574-A1 | Novel cyclic compound having 4-pyridylalkylthio group having substituted or unsubstituted amino group introduced therein | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149574-A1 | Novel cyclic compound having 4-pyridylalkylthio group having substituted or unsubstituted amino group introduced therein | FLT4, FLT1, TIE1 | KMT2A 2966/4885KDR 12/4885FLT1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.