Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928816 | 1.00 | TPMT (0.42) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL3548180 | 0.76 | TPMT (0.53) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL3548177 | 0.76 | TPMT (0.53) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL5216689 | 0.70 | TPMT (0.41) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL5216674 | 0.70 | TPMT (0.41) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL5216671 | 0.70 | TPMT (0.41) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL3637333 | 0.68 | TNFRSF1A (0.56) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL10323913 | 0.66 | TPMT (0.41) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL22466026 | 0.66 | HTT (0.47) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL29381794 | 0.66 | HTT (0.47) | TPMTCA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494673-B1 | Method for treatment of kidney and/or urinary system stones | TORRES PHILLIP | 2009-02-24 | — | — | US | disclosed |