SCHEMBL392907

SCHEMBL392907

CC(=Cc1cccc(S(=O)(=O)Nc2cccc3ccccc23)c1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.61
RECQL P46063 1/20 0.59
MEN1 O00255 4/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPT P10636 2/20 0.53
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
MCL1 Q07820 2/20 0.46
METAP2 P50579 1/20 0.46
METAP1 P53582 1/20 0.46
AKR1C3 P42330 1/20 0.46
KEAP1 Q14145 2/20 0.45
SLC16A3 O15427 3/20 0.43
NFE2L2 Q16236 1/20 0.43
HDAC1 Q13547 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
G6PD P11413 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396988 0.83 HDAC1 (0.60) KMT2AMEN1ALDH1A1MAPTAKR1C3
SCHEMBL396989 0.83 HDAC1 (0.60) KMT2AMEN1ALDH1A1MAPTAKR1C3
SCHEMBL393832 0.81 AKR1C3 (0.61) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL1403105 0.81 KMT2A (0.64) KMT2ARECQLMEN1ALDH1A1MAPT
SCHEMBL1403106 0.81 KMT2A (0.64) KMT2ARECQLMEN1ALDH1A1MAPT
SCHEMBL398494 0.79 AKR1C3 (0.53) MAPTLMNAAKR1C3HDAC1
SCHEMBL398495 0.79 AKR1C3 (0.53) MAPTLMNAAKR1C3HDAC1
SCHEMBL1403142 0.78 KMT2A (0.57) KMT2ARECQLMEN1ALDH1A1MAPT
SCHEMBL1403143 0.78 KMT2A (0.57) KMT2ARECQLMEN1ALDH1A1MAPT
SCHEMBL396885 0.78 HDAC1 (0.60) KMT2AMEN1ALDH1A1HTTAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed