SCHEMBL3929242

SCHEMBL3929242

CCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@@H](CO)C(=O)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SIRT2 Q8IXJ6 9/20 0.46
▸ SIRT1 Q96EB6 6/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ HPGD P15428 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ SIRT3 Q9NTG7 3/20 0.46
▸ TLR2 O60603 3/20 0.44
▸ MAPT P10636 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ MGLL Q99685 1/20 0.43
▸ PRKCA P17252 1/20 0.42
▸ PRKCE Q02156 1/20 0.42
▸ PRKCQ Q04759 1/20 0.42
▸ PRKCD Q05655 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3939473 1.00 SIRT2 (0.46) SIRT2SIRT1MEN1ALDH1A1HPGD
SCHEMBL3936778 1.00 SIRT2 (0.46) SIRT2SIRT1MEN1ALDH1A1HPGD
SCHEMBL3939841 1.00 SIRT2 (0.46) SIRT2SIRT1MEN1ALDH1A1HPGD
SCHEMBL3930451 1.00 SIRT2 (0.46) SIRT2SIRT1MEN1ALDH1A1HPGD
SCHEMBL3929753 1.00 SIRT2 (0.46) SIRT2SIRT1MEN1ALDH1A1HPGD
SCHEMBL3937776 1.00 SIRT2 (0.46) SIRT2SIRT1MEN1ALDH1A1HPGD
SCHEMBL3936777 1.00 SIRT2 (0.46) SIRT2SIRT1MEN1ALDH1A1HPGD
SCHEMBL2678812 0.88 SIRT2 (0.51) SIRT2SIRT1MEN1ALDH1A1HPGD
SCHEMBL28993230 0.87 SIRT2 (0.45) SIRT2SIRT1MEN1ALDH1A1HPGD
SCHEMBL11196365 0.85 MEN1 (0.52) SIRT2SIRT1MEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7541020-B2 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION (US) 2009-06-02 — — US disclosed
US-7063967-B2 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION (US) 2006-06-20 — — US disclosed
EP-0983286-B1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORP (US) 2004-07-28 — — EP disclosed
US-6764840-B2 AUGMENT ANTIBODY PRODUCTION IN IMMUNIZED ANIMALS AS WELL AS STIMULATE CYTOKINE PRODUCTION AND ACTIVATE MACROPHAGES. CORIXA CORPORATION 2004-07-20 — — US disclosed
US-20030199460-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION (US) 2003-10-23 — — US disclosed
US-20030092643-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2003-05-15 — — US disclosed
EP-1230250-A2 AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 2002-08-14 — — EP disclosed
US-20020048588-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2002-04-25 — — US disclosed
US-6355257-B1 Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2002-03-12 — — US disclosed
US-6303347-B1 VACCINES CORIXA CORPORATION 2001-10-16 — — US disclosed
WO-2001034617-A2 AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 2001-05-17 — — WO disclosed
US-6113918-A IMMUNOLOGY RIBI IMMUNOCHEM RESEARCH, INC. (US) 2000-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199460-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors DNPEP, CD68, MGAT3 SIRT2 4338/4885SIRT1 4744/4885MEN1 4284/4885
US-20020048588-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors DNPEP, CD68, MGAT3 SIRT2 4253/4885SIRT1 4700/4885MEN1 4335/4885
US-20030092643-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors DNPEP, CD68, MGAT3 SIRT2 4338/4885SIRT1 4744/4885MEN1 4284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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