Tetrylammonium

Tetrylammonium

SCHEMBL3929499

CC(=O)[O-].CC[N+](CC)(CC)CC.O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
TSHR P16473 2/20 0.50
NFKB1 P19838 2/20 0.50
KCNA1 Q09470 1/20 0.50
KDM4E B2RXH2 1/20 0.47
PMP22 Q01453 1/20 0.47
ATM Q13315 1/20 0.47
CES1 P23141 2/20 0.38
CA4 P22748 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
FFAR3 O14843 2/20 0.36
HDAC3 O15379 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
BBOX1 O75936 3/20 0.36
CES2 O00748 1/20 0.33
CYP3A4 P08684 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrylammonium SCHEMBL9312731 1.00 CA1 (0.50) CA1TSHRNFKB1KCNA1KDM4E
Tetrylammonium SCHEMBL3361488 1.00 CA1 (0.50) CA1TSHRNFKB1KCNA1KDM4E
Tetrylammonium SCHEMBL1870055 1.00 CA1 (0.50) CA1TSHRNFKB1KCNA1KDM4E
Tetrylammonium SCHEMBL27456144 0.97 CA1 (0.47) CA1TSHRNFKB1KCNA1KDM4E
Tetrylammonium SCHEMBL30349943 0.97 CA1 (0.53) CA1TSHRNFKB1KCNA1KDM4E
Tetrylammonium SCHEMBL49874 0.97 CA1 (0.53) CA1TSHRNFKB1KCNA1KDM4E
Tetrylammonium SCHEMBL3242574 0.94 CA1 (0.50) CA1TSHRNFKB1KCNA1KDM4E
Tetrylammonium SCHEMBL29227388 0.91 CA1 (0.47) CA1TSHRNFKB1KCNA1KDM4E
Tetrylammonium SCHEMBL16415823 0.89 CA1 (0.40) CA1TSHRNFKB1KCNA1KDM4E
Tetrylammonium SCHEMBL21268041 0.88 CA1 (0.44) CA1TSHRNFKB1KCNA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2038293-A1 NON-ANIMAL BASED LACTOSE Alberta Research Council, Inc. (CA) 2009-03-25 EP claimed
WO-2008000082-A1 NON-ANIMAL BASED LACTOSE ALBERTA RESEARCH COUNCIL INC. (CA) 2008-01-03 WO claimed
EP-2038293-A1 NON-ANIMAL BASED LACTOSE Alberta Research Council, Inc. (CA) 2009-03-25 EP disclosed
WO-2008000082-A1 NON-ANIMAL BASED LACTOSE ALBERTA RESEARCH COUNCIL INC. (CA) 2008-01-03 WO disclosed
EP-0916685-B1 Branching agents for reactive extrusion GEN ELECTRIC (US) 2005-09-28 EP disclosed
US-6316405-B1 CYCLOSPORIN A, POLYPEPTIDES, COMPONENT OF AMYLOID PLAQUES FOUND IN NEUROLOGICAL DISORDERS SUCH AS ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, AND AMYOTROPHIC LATERAL SCLEROSIS. THE CONJUGATES ARE USEFUL IN THE TREATMENT OF NEUROLOGICAL WISCONSIN ALUMNI RESEARCH FOUNDATION 2001-11-13 US disclosed
US-6270957-B1 USEFUL IN THE TREATMENT AND PREVENTION OF HIV (HUMAN IMMUNODEFICIENCY VIRUS)-MEDIATED DISORDERS, INCLUDING AIDS (ACQUIRE IMMUNODEFICIENCY SYNDROME) WISCONSIN ALUMNI RESEARCH FOUNDATION 2001-08-07 US disclosed
CN-1067396-C Processes for producing N,N'-diffluorodiazoniabicyclo-alkane salts, intermediates int he synthesis of the same, target products, and application of the target products DAIKIN IND LTD (JP) 2001-06-20 CN disclosed
US-6087468-A CROSSLINKING A POLYCARBONATE, ESTER INTERCHANGE, REMOVING SOLVENT AND MELT BLENDING GENERAL ELECTRIC COMPANY (US) 2000-07-11 US disclosed
EP-0916685-A1 Branching agents for reactive extrusion GENERAL ELECTRIC COMPANY (US) 1999-05-19 EP disclosed
US-5892035-A FLUORINATING THE CORRESPONDING DIAZABICYCLOALKALINE COMPOUND DAIKIN INDUSTRIES LTD. (JP) 1999-04-06 US disclosed
WO-1999010374-A1 CYCLOSPORIN A CONJUGATES AND USES THEREFOR WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1999-03-04 WO disclosed
WO-1999010373-A1 NON-IMMUNOSUPPRESSIVE CYCLOSPORINS AND THEIR USE IN THE PREVENTION AND TREATMENT OF HIV INFECTION WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1999-03-04 WO disclosed
CN-1165516-A Processes for producing N,N'-diffluorodiazoniabicyclo-alkane salts, intermediates int he synthesis of the same, target products, and application of the target products DAIKIN IND LTD (JP) 1997-11-19 CN disclosed
EP-0785199-A1 PROCESSES FOR PRODUCING N,N'-DIFLUORODIAZONIABICYCLO-ALKANE SALTS, INTERMEDIATES IN THE SYNTHESIS OF THE SAME, TARGET PRODUCTS, AND APPLICATION OF THE TARGET PRODUCTS DAIKIN INDUSTRIES, LIMITED (JP) 1997-07-23 EP disclosed
EP-0264183-B1 DERIVATIVES OF 5-METHYL-10,11-DIHYDRO-5H-DIBENZO-(A,D) CYCLOHEPTEN-5,10-IMINE MERCK & CO. INC. (US) 1992-01-15 EP disclosed
US-4870079-A ANTICONVULSANTS, ANTAGONISTS OF N-METHYL-D-ASPARTATE MERCK & CO., INC. (US) 1989-09-26 US disclosed
EP-0264183-A1 Derivatives of 5-methyl-10,11-dihydro-5H-dibenzo-(a,d) cyclohepten-5,10-imine MERCK & CO. INC. (US) 1988-04-20 EP disclosed