SCHEMBL3929624

SCHEMBL3929624

CCCCCCCCCCCCCCCCC(CCCCCCCCCCCCC)C(=O)Oc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC2 Q9UIJ5 1/20 0.49
FAAH O00519 6/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
ATM Q13315 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CNR2 P34972 1/20 0.47
HDAC8 Q9BY41 4/20 0.46
HDAC3 O15379 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP12 P39900 1/20 0.46
GAA P10253 1/20 0.46
XBP1 P17861 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC2 Q92769 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11296486 1.00 ZDHHC2 (0.49) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL29163411 1.00 ZDHHC2 (0.49) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL2291169 0.98 ATM (0.48) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL2290979 0.98 ATM (0.48) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL27915850 0.98 ATM (0.48) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL2296516 0.97 HDAC8 (0.47) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL2296150 0.97 HDAC8 (0.47) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL2288531 0.97 ATM (0.49) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL2293062 0.95 HDAC8 (0.48) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL28714996 0.94 ATM (0.53) ZDHHC2FAAHPRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481157-B2 Melt extruded fibers and methods of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-09 US disclosed
EP-2038457-A1 PARTICULATE-LOADED POLYMER FIBERS AND EXTRUSION METHODS 3M Innovative Properties Company (US) 2009-03-25 EP disclosed
US-7476352-B2 Lubricated flow fiber extrusion 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-01-13 US disclosed
US-20080003430-A1 PARTICULATE-LOADED POLYMER FIBERS AND EXTRUSION METHODS 3M INNOVATIVE PROPERTIES COMPANY 2008-01-03 US disclosed
WO-2008002724-A1 PARTICULATE-LOADED POLYMER FIBERS AND EXTRUSION METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-01-03 WO disclosed
US-20070154708-A1 MELT EXTRUDED FIBERS AND METHODS OF MAKING THE SAME 3M INOVATIVE PROPERTIES COMPANY 2007-07-05 US disclosed
EP-1753898-A1 LUBRICATED FLOW FIBER EXTRUSION 3M Innovative Properties Company (US) 2007-02-21 EP disclosed
WO-2005116308-A1 LUBRICATED FLOW FIBER EXTRUSION 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-12-08 WO disclosed
US-20050258562-A1 Lubricated flow fiber extrusion 3M INNOVATIVE PROPERTIES COMPANY 2005-11-24 US disclosed
US-4519909-A HOMOGENEOUS, THREE-DIMENSIONAL POLYMER STRUCTURE AKZONA INCORPORATED (US) 1985-05-28 US disclosed
US-4247498-A THERMOPLASTICS AKZONA INCORPORATED (US) 1981-01-27 US disclosed