Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094117 | 0.95 | CXCR4 (0.50) | SMN1; SMN2MAPTLIN28ATDP1CXCR4 | |
| SCHEMBL2474794 | 0.95 | CXCR4 (0.50) | SMN1; SMN2MAPTLIN28ATDP1CXCR4 | |
| SCHEMBL8507962 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTLIN28ATDP1HRH1 | |
| SCHEMBL12453816 | 0.91 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTLIN28ATDP1KMT2A | |
| SCHEMBL8211406 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTLIN28ATDP1KMT2A | |
| SCHEMBL8208011 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTLIN28ATDP1KMT2A | |
| SCHEMBL2818579 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTLIN28ATDP1KMT2A | |
| SCHEMBL29574935 | 0.87 | SMN1; SMN2 (0.71) | SMN1; SMN2MAPTLIN28ATDP1KMT2A | |
| SCHEMBL8208243 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTLIN28ATDP1KMT2A | |
| SCHEMBL8209122 | 0.87 | TDP1 (0.66) | SMN1; SMN2MAPTLIN28ATDP1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585852-B2 | Cobalamine derivatives useful for diagnosis and treatment of abnormal cellular proliferation | SOLIDAGO AG (CH) | 2009-09-08 | — | — | US | disclosed |
| US-20070155692-A1 | Cobalamine derivatives useful for diagnosis and treatment of abnormal cellular proliferation | SOLIDAGO AG (CH) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155692-A1 | Cobalamine derivatives useful for diagnosis and treatment of abnormal cellular proliferation | MMAB, SLC19A2, FABP2 | SMN1; SMN2 2291/4885MAPT 3745/4885LIN28A 2262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.