Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21816341 | 1.00 | GAA (0.47) | GAAMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL3930237 | 1.00 | GAA (0.47) | GAAMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL10826850 | 0.88 | GAA (0.47) | GAAMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL10826852 | 0.88 | GAA (0.47) | GAAMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL8476490 | 0.84 | GAA (0.66) | GAAMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL10736348 | 0.81 | GAA (0.43) | GAAMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL10736360 | 0.81 | GAA (0.43) | GAAMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL3118758 | 0.81 | SMN1; SMN2 (0.55) | GAAMAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL3118762 | 0.81 | SMN1; SMN2 (0.55) | GAAMAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL3466393 | 0.81 | SMN1; SMN2 (0.55) | GAAMAPTLMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61171475-A | — | — | None | — | — | JP | disclosed |
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2009011850-A2 | NOVEL THERAPEUTIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2009-01-22 | — | — | WO | disclosed |
| US-4902805-A | SELECTIVITY TO WEEDS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-02-20 | — | — | US | disclosed |
| JP-S61171475-A | PRODUCTION OF 1,2,4-TRIAZOLE-3-CARBOXYLIC ACID DERIVATIVE | KUREHA CHEM IND CO LTD | 1986-08-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | GAA 872/4885MAPT 3755/4885LMNA 3011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.