Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 11/20 | 0.39 |
| ▸ | OGA | O60502 | 7/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943888 | 1.00 | AOC3 (0.39) | AOC3OGAPDCD1CD274CDK4 | |
| SCHEMBL4863748 | 0.95 | OGA (0.41) | AOC3OGA | |
| SCHEMBL4874389 | 0.95 | OGA (0.41) | AOC3OGA | |
| SCHEMBL4873154 | 0.95 | AOC3 (0.40) | AOC3OGA | |
| SCHEMBL3933517 | 0.90 | AOC3 (0.41) | AOC3OGA | |
| SCHEMBL3941136 | 0.90 | AOC3 (0.41) | AOC3OGA | |
| SCHEMBL4875485 | 0.88 | AOC3 (0.44) | AOC3OGA | |
| SCHEMBL5669927 | 0.87 | OGA (0.44) | AOC3OGA | |
| SCHEMBL5551593 | 0.87 | AOC3 (0.37) | AOC3OGA | |
| SCHEMBL5551601 | 0.87 | AOC3 (0.37) | AOC3OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786792-B1 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC (JP) | 2009-04-08 | — | — | EP | disclosed |