Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.51 |
| ▸ | CNR1 | P21554 | 14/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932105 | 0.84 | KDM4E (0.48) | CNR2CNR1LMNACYP1A2CYP3A4 | |
| SCHEMBL3925621 | 0.81 | MAP4K4 (0.43) | CNR2ALDH1A1AKT1AKT2AKT3 | |
| SCHEMBL30333588 | 0.81 | MAP4K4 (0.43) | CNR2ALDH1A1AKT1AKT2AKT3 | |
| SCHEMBL3930200 | 0.80 | LIMK2 (0.54) | CNR2CNR1ALDH1A1MAPK1 | |
| SCHEMBL3933805 | 0.79 | KIT (0.49) | LMNACYP1A2CYP3A4CLK4USP2 | |
| SCHEMBL3931531 | 0.78 | MKNK2 (0.44) | LMNAUSP2TSHRMAPK1 | |
| SCHEMBL3919894 | 0.76 | NEK2 (0.43) | ALDH1A1AKT1 | |
| SCHEMBL3925100 | 0.76 | CYP1A2 (0.46) | LMNACYP1A2CYP3A4CYP2C19CLK4 | |
| SCHEMBL20304708 | 0.73 | CNR1 (0.82) | CNR2CNR1 | |
| SCHEMBL16637970 | 0.72 | PDGFRB (0.51) | LMNACYP1A2CYP3A4CYP2C19CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009003669-A2 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT | 4 AZA IP NV (BE) | 2009-01-08 | — | — | WO | claimed |