Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396539 | 0.94 | TDP1 (0.41) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL2367678 | 0.90 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL394445 | 0.88 | TDP1 (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL5606079 | 0.88 | TDP1 (0.45) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL13863128 | 0.86 | TDP1 (0.41) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL2368083 | 0.85 | TDP1 (0.41) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL14181196 | 0.85 | TDP1 (0.41) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL11072800 | 0.85 | POLB (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL12977076 | 0.84 | TDP1 (0.40) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL26282469 | 0.83 | TDP1 (0.48) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110697-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8101789-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| EP-2125833-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-2125834-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100029972-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |
| US-7169874-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169874-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2007-01-30 | — | — | US | disclosed |
| US-7138440-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2006-11-21 | — | — | US | disclosed |
| US-7101949-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2006-09-05 | — | — | US | disclosed |
| US-6908978-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2005-06-21 | — | — | US | disclosed |
| US-20050131191-A1 | High refractive index polymeric siloxysilane compositions | SALAMONE JOSEPH C (US) | 2005-06-16 | — | — | US | disclosed |
| US-20050131189-A1 | High refractive index polymeric siloxysilane compositions | SALIX PHARMACEUTICALS, LTD. | 2005-06-16 | — | — | US | disclosed |
| US-20050127557-A1 | High refractive index polymeric siloxysilane compositions | SOLTA MEDICAL, INC. | 2005-06-16 | — | — | US | disclosed |
| EP-1465903-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2004-10-13 | — | — | EP | disclosed |
| EP-1448572-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20030109661-A1 | High refractive index polymeric siloxysilane compositions | BAUSCH HEALTH US, LLC | 2003-06-12 | — | — | US | disclosed |
| US-20030100697-A1 | High refractive index polymeric siloxysilane compositions | SALIX PHARMACEUTICALS, INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003040158-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003040157-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |