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Carbamic Acid

Carbamic Acid

SCHEMBL3933072

CC(=O)Nc1nc(CCc2ccc(NC=NC(=O)O)cc2)c(Cc2ccc(S(N)(=O)=O)cc2)s1.NC(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ AOC3 Q16853 16/20 0.69
▸ CA1 P00915 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ PIK3CD O00329 1/20 0.40
▸ PIK3CA P42336 1/20 0.40
▸ PIK3CB P42338 1/20 0.40
▸ PIK3CG P48736 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL4987900 0.93 AOC3 (0.59) AOC3
Carbamic Acid SCHEMBL4986143 0.93 AOC3 (0.69) AOC3PIK3CDPIK3CAPIK3CBPIK3CG
Carbamic Acid SCHEMBL3937295 0.91 AOC3 (0.70) AOC3
Carbamic Acid SCHEMBL4873897 0.91 AOC3 (0.68) AOC3
Carbamic Acid SCHEMBL4875636 0.88 AOC3 (0.68) AOC3PIK3CDPIK3CAPIK3CBPIK3CG
Carbamic Acid SCHEMBL4984600 0.88 AOC3 (0.55) AOC3
Carbamic Acid SCHEMBL4874115 0.87 AOC3 (0.56) AOC3
Carbamic Acid SCHEMBL4867198 0.87 AOC3 (0.56) AOC3
Carbamic Acid SCHEMBL3939317 0.86 AOC3 (0.71) AOC3PIK3CGALDH1A1
Carbamic Acid SCHEMBL3933648 0.86 AOC3 (0.54) AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1786792-B1 THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY ASTELLAS PHARMA INC (JP) 2009-04-08 — — EP disclosed