SCHEMBL3933115

SCHEMBL3933115

CCc1csc([C@H](Cc2ccc(NS(=O)(=O)O)cc2)NC(=O)C(C(=O)OC)c2ccccc2)n1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPRB P23467 20/20 0.75
PTPN1 P18031 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3581514 1.00 PTPRB (0.75) PTPRBPTPN1
SCHEMBL3569778 0.92 PTPRB (0.76) PTPRBPTPN1
SCHEMBL3569776 0.92 PTPRB (0.76) PTPRBPTPN1
SCHEMBL3581560 0.90 PTPRB (0.81) PTPRBPTPN1
SCHEMBL3581552 0.90 PTPRB (0.81) PTPRBPTPN1
SCHEMBL20474090 0.88 PTPRB (0.77) PTPRBPTPN1
SCHEMBL468124 0.88 PTPRB (0.77) PTPRBPTPN1
SCHEMBL468123 0.88 PTPRB (0.77) PTPRBPTPN1
SCHEMBL3604112 0.87 PTPRB (0.79) PTPRBPTPN1
SCHEMBL3604107 0.87 PTPRB (0.79) PTPRBPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2041102-A2 HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE The Procter & Gamble Company (US) 2009-04-01 EP disclosed
WO-2008002569-A2 HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THE PROCTER & GAMBLE COMPANY (US) 2008-01-03 WO disclosed