Carbamic Acid

Carbamic Acid

SCHEMBL3933522

CNC(=O)[C@@H]1CCN(Cc2sc(NC(C)=O)nc2CCc2ccc(NC=NC(=O)O)cc2)C1.NC(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 14/20 0.44
OGA O60502 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL3941141 1.00 AOC3 (0.44) AOC3OGA
Carbamic Acid SCHEMBL5671197 0.96 OGA (0.43) AOC3OGA
Carbamic Acid SCHEMBL4870886 0.96 OGA (0.43) AOC3OGA
Carbamic Acid SCHEMBL5669929 0.96 AOC3 (0.45) AOC3OGA
Carbamic Acid SCHEMBL3931809 0.91 AOC3 (0.42) AOC3OGA
Carbamic Acid SCHEMBL3943894 0.91 AOC3 (0.42) AOC3OGA
Carbamic Acid SCHEMBL4875495 0.90 AOC3 (0.45) AOC3OGA
Carbamic Acid SCHEMBL4873162 0.88 AOC3 (0.43) AOC3OGA
Carbamic Acid SCHEMBL4863758 0.86 AOC3 (0.41) AOC3OGA
Carbamic Acid SCHEMBL4874401 0.86 AOC3 (0.41) AOC3OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1786792-B1 THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY ASTELLAS PHARMA INC (JP) 2009-04-08 EP disclosed