Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.56 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.42 |
| ▸ | CPB1 | P15086 | 3/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AOC1 | P19801 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14415992 | 0.81 | HRH4 (0.61) | HRH4HRH3CPB2CPB1HRH2 | |
| SCHEMBL11667436 | 0.78 | HRH3 (0.58) | HRH4HRH3CPB2CPB1HRH2 | |
| SCHEMBL14415989 | 0.78 | HRH4 (0.62) | HRH4HRH3CPB2CPB1LMNA | |
| SCHEMBL14415990 | 0.75 | HRH3 (0.54) | HRH4HRH3CPB2CPB1 | |
| SCHEMBL14415987 | 0.74 | CPA1 (0.57) | HRH4HRH3CPB2CPB1 | |
| SCHEMBL25374785 | 0.72 | — | — | |
| SCHEMBL20307127 | 0.72 | — | — | |
| SCHEMBL3926222 | 0.72 | — | — | |
| SCHEMBL28181817 | 0.71 | HRH3 (0.53) | HRH4HRH3CPB2CPB1TSHR | |
| Hydrochloric Acid SCHEMBL1696891 | 0.71 | HRH4 (0.96) | HRH4HRH3CPB2CPB1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041132-A2 | NEW COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008003766-A2 | 4-HETER0CYCL0ALKYLPYRI(MI)DINES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |