Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.58 |
| ▸ | PPARD | Q03181 | 11/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934507 | 1.00 | PPARA (0.58) | PPARAPPARDPPARGKCNH2MEN1 | |
| SCHEMBL14491083 | 0.89 | PPARA (0.60) | PPARAPPARDPPARGKCNH2MEN1 | |
| SCHEMBL11893170 | 0.86 | PPARA (0.60) | PPARAPPARDPPARGKCNH2MEN1 | |
| SCHEMBL4459084 | 0.86 | PPARA (0.60) | PPARAPPARDPPARGKCNH2MEN1 | |
| SCHEMBL13359189 | 0.86 | MAOB (0.61) | PPARAPPARDPPARGKCNH2CTSL | |
| SCHEMBL13764697 | 0.82 | PPARA (0.77) | PPARAPPARDPPARGKCNH2MEN1 | |
| SCHEMBL15163347 | 0.82 | PPARA (0.77) | PPARAPPARDPPARGKCNH2MEN1 | |
| SCHEMBL814527 | 0.81 | PPARA (0.67) | PPARAPPARDPPARGKCNH2ALDH1A1 | |
| SCHEMBL814579 | 0.80 | PPARA (0.58) | PPARAPPARDPPARGKCNH2 | |
| SCHEMBL814554 | 0.80 | PPARA (0.61) | PPARAPPARDPPARGKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046716-B1 | SUBSTITUTED 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | GENFIT (FR) | 2013-08-14 | — | — | EP | disclosed |
| EP-2046716-A1 | SUBSTITUTED 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | Genfit (FR) | 2009-04-15 | — | — | EP | disclosed |
| WO-2007147880-A1 | SUBSTITUTED 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | GENFIT (FR) | 2007-12-27 | — | — | WO | disclosed |