Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | BLM | P54132 | 3/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | SHBG | P04278 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.62 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.62 |
| ▸ | SNCA | P37840 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.61 |
| ▸ | PGR | P06401 | 3/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.61 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932821 | 1.00 | CYP19A1 (0.65) | CYP19A1SMN1; SMN2ALDH1A1MAPK1BLM | |
| SCHEMBL3934603 | 1.00 | CYP19A1 (0.65) | CYP19A1SMN1; SMN2ALDH1A1MAPK1BLM | |
| SCHEMBL14546354 | 0.88 | SMN1; SMN2 (0.71) | CYP19A1SMN1; SMN2ALDH1A1MAPK1BLM | |
| SCHEMBL12153590 | 0.88 | SMN1; SMN2 (0.71) | CYP19A1SMN1; SMN2ALDH1A1MAPK1BLM | |
| SCHEMBL5683193 | 0.88 | SMN1; SMN2 (0.71) | CYP19A1SMN1; SMN2ALDH1A1MAPK1BLM | |
| SCHEMBL12153531 | 0.88 | SMN1; SMN2 (0.71) | CYP19A1SMN1; SMN2ALDH1A1MAPK1BLM | |
| SCHEMBL16842389 | 0.88 | SMN1; SMN2 (0.71) | CYP19A1SMN1; SMN2ALDH1A1MAPK1BLM | |
| SCHEMBL5683195 | 0.88 | SMN1; SMN2 (0.71) | CYP19A1SMN1; SMN2ALDH1A1MAPK1BLM | |
| SCHEMBL12153463 | 0.88 | SMN1; SMN2 (0.71) | CYP19A1SMN1; SMN2ALDH1A1MAPK1BLM | |
| SCHEMBL3933487 | 0.87 | CYP19A1 (0.76) | CYP19A1SMN1; SMN2ALDH1A1MAPK1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976997-B1 | PROCESS FOR THE PREPARATION OF 11BETA-HYDR0XY-9BETA,10ALPHA-STEROIDS EMPLOYING AMYCOLATOPSIS MEDITERRANEI CELLS | SOLVAY PHARM GMBH (DE) | 2009-04-08 | — | — | EP | disclosed |
| EP-1976997-A1 | PROCESS FOR THE PREPARATION OF 11BETA-HYDR0XY-9BETA, 10ALPHA -STEROIDS EMPLOYING AMYCOLATOPSIS MEDITERRANEI CELLS | Solvay Pharmaceuticals GmbH (DE) | 2008-10-08 | — | — | EP | disclosed |
| US-20070212751-A1 | Microbial method for the 11beta hydroxylation of 9beta, 10alpha-steriods | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-09-13 | — | — | US | disclosed |
| WO-2007082891-A1 | PROCESS FOR THE PREPARATION OF 11BETA-HYDR0XY-9BETA, 10ALPHA -STEROIDS EMPLOYING AMYCOLATOPSIS MEDITERRANEI CELLS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-07-26 | — | — | WO | disclosed |