SCHEMBL3935420

SCHEMBL3935420

OC[C@H]1O[C@@H](c2ccc(Cl)c(Cc3cc4ccccc4s3)c2)[C@H](O)[C@@H](O)[C@H]1F

nearest known ligand 0.83

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.83
SLC5A1 P13866 5/20 0.67
CHRM1 P11229 1/20 0.67
ADRA1A P35348 1/20 0.67
SLC6A3 Q01959 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14304733 1.00 SLC5A2 (0.83) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL12782042 1.00 SLC5A2 (0.83) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL147932 0.91 SLC5A2 (1.00) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL19312345 0.91 SLC5A2 (1.00) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL9975492 0.91 SLC5A2 (1.00) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL9973937 0.91 SLC5A2 (1.00) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL12782038 0.82 SLC5A2 (0.61) SLC5A2SLC5A1
SCHEMBL14310972 0.81 SLC5A2 (0.68) SLC5A2SLC5A1SLC6A3
SCHEMBL14302420 0.81 SLC5A2 (0.68) SLC5A2SLC5A1SLC6A3
SCHEMBL3936832 0.81 SLC5A2 (0.68) SLC5A2SLC5A1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2046346-A1 NOVEL SGLT INHIBITORS Mitsubishi Tanabe Pharma Corporation (JP) 2009-04-15 EP claimed
US-20080027014-A1 Novel SGLT inhibitors TANABE SEIYAKU CO., LTD. 2008-01-31 US claimed
WO-2008013321-A1 NOVEL SGLT INHIBITORS MITSUBISHI TANABE PHARMA CORPORATION (JP) 2008-01-31 WO claimed
EP-2046346-A1 NOVEL SGLT INHIBITORS Mitsubishi Tanabe Pharma Corporation (JP) 2009-04-15 EP disclosed
US-20080027014-A1 Novel SGLT inhibitors TANABE SEIYAKU CO., LTD. 2008-01-31 US disclosed
WO-2008013321-A1 NOVEL SGLT INHIBITORS MITSUBISHI TANABE PHARMA CORPORATION (JP) 2008-01-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027014-A1 Novel SGLT inhibitors SLC5A1, SLC5A2, SLC10A1 SLC5A2 2/4885SLC5A1 1/4885CHRM1 4788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.