⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1228214 | 1.00 | — | — | |
| SCHEMBL11297533 | 1.00 | F2 (1.00) | — | |
| SCHEMBL11293968 | 1.00 | F2 (1.00) | — | |
| SCHEMBL11295735 | 1.00 | F2 (1.00) | — | |
| SCHEMBL821192 | 1.00 | F2 (1.00) | — | |
| SCHEMBL11288384 | 1.00 | F2 (1.00) | — | |
| SCHEMBL8281615 | 1.00 | F2 (1.00) | — | |
| SCHEMBL11295249 | 1.00 | F2 (1.00) | — | |
| Hydrochloric Acid SCHEMBL6420004 | 0.97 | F2 (0.94) | — | |
| Hydrochloric Acid SCHEMBL6422667 | 0.97 | F2 (0.94) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101896485-A | Novel compounds of reverse turn mimetics and the use thereof (3) | CHOONGWAE PHARMA CORP | 2010-11-24 | — | — | CN | claimed |
| CN-101827849-A | Novel compounds of reverse turn mimetics and the use thereof (1) | CHOONGWAE PHARMA CORP | 2010-09-08 | — | — | CN | claimed |
| CN-101827850-A | Novel compounds of reverse turn mimetics and the use thereof (2) | CHOONGWAE PHARMA CORP | 2010-09-08 | — | — | CN | claimed |
| CN-101495120-A | Composition for induction or inhibition of stem cell differentiation | CHOONGWAE PHARMA CORP (KR) | 2009-07-29 | — | — | CN | claimed |
| CN-1942472-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2007-04-04 | — | — | CN | claimed |
| CN-1872856-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-12-06 | — | — | CN | claimed |
| CN-1872857-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-12-06 | — | — | CN | claimed |
| CN-1871239-A | Modulation of beta-catenin/tcf-activated transcription | CHOONGWAE PHARMA CORP (KR) | 2006-11-29 | — | — | CN | claimed |
| CN-1802378-A | Beta-strand mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-07-12 | — | — | CN | claimed |
| CN-1798746-A | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-07-05 | — | — | CN | claimed |
| CN-1585770-A | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2005-02-23 | — | — | CN | claimed |
| CN-1353701-A | Peptidyl heterocyclic ketones useful as tryptase inhibitors | ORTHO MCNEIL PHARM INC (US) | 2002-06-12 | — | — | CN | claimed |
| US-5373008-A | Phenylamidine and phenylguanidine derivatives and their use as anti-diabetic agents | THE BOOTS COMPANT PLC. (GB) | 1994-12-13 | — | — | US | claimed |
| EP-0536151-B1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | BOOTS CO PLC (GB) | 1994-09-14 | — | — | EP | claimed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| WO-1992000273-A1 | ORTHOSUBSTITUTED BIPHENYL AMIDINE AND BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | THE BOOTS COMPANY PLC (GB) | 1992-01-09 | — | — | WO | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| CN-117083065-A | Novel treatment and prevention of sarcopenia-related diseases and the like | 庆应义塾 | 2023-11-17 | — | — | CN | disclosed |
| WO-1992000273-A1 | ORTHOSUBSTITUTED BIPHENYL AMIDINE AND BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | THE BOOTS COMPANY PLC (GB) | 1992-01-09 | — | — | WO | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |