Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 16/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986138 | 0.89 | AOC3 (0.65) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3938903 | 0.89 | AOC3 (0.65) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4873920 | 0.87 | AOC3 (0.72) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5550418 | 0.85 | AOC3 (0.57) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL14019612 | 0.84 | AOC3 (0.71) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL3930741 | 0.84 | AOC3 (0.70) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4875627 | 0.84 | AOC3 (0.64) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL14365397 | 0.83 | AOC3 (0.67) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL3935924 | 0.83 | AOC3 (0.66) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4874225 | 0.82 | AOC3 (0.70) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786792-B1 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC (JP) | 2009-04-08 | — | — | EP | disclosed |