Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 18/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365314 | 0.92 | P2RY12 (0.64) | P2RY12KDM4EMAPTALDH1A1 | |
| SCHEMBL4351349 | 0.88 | P2RY12 (0.59) | P2RY12KDM4EMAPTALDH1A1 | |
| SCHEMBL3930910 | 0.82 | P2RY12 (0.57) | P2RY12KDM4EALDH1A1 | |
| SCHEMBL3941792 | 0.79 | P2RY12 (0.58) | P2RY12KDM4EMAPTALDH1A1 | |
| SCHEMBL3936294 | 0.78 | P2RY12 (0.59) | P2RY12KDM4EMAPTALDH1A1 | |
| SCHEMBL3584223 | 0.78 | P2RY12 (0.82) | P2RY12ALDH1A1 | |
| SCHEMBL3578444 | 0.78 | P2RY12 (0.82) | P2RY12 | |
| SCHEMBL3930016 | 0.77 | KDM4E (0.59) | P2RY12KDM4EMAPTALDH1A1 | |
| SCHEMBL3932387 | 0.77 | P2RY12 (0.66) | P2RY12KDM4EMAPTALDH1A1 | |
| SCHEMBL4011120 | 0.72 | P2RY12 (0.62) | P2RY12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044024-A1 | NEW PYRIDINE ANALOGUES | AstraZeneca AB (SE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008004943-A1 | NEW PYRIDINE ANALOGUES | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | disclosed |