Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699226 | 0.99 | KDR (0.52) | KDRPSMB8NPC1RAB9ACYP1A2 | |
| SCHEMBL6933152 | 0.86 | GAA (0.50) | KDRPSMB8NPC1RAB9APOLB | |
| SCHEMBL24863091 | 0.86 | HTT (0.46) | KDRPOLBHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL19977100 | 0.84 | SMN1; SMN2 (0.43) | KDRPSMB8NPC1RAB9AHDAC1 | |
| SCHEMBL28435031 | 0.83 | GAA (0.45) | CYP1A2CYP3A4POLBALDH1A1PARP1 | |
| SCHEMBL30776547 | 0.83 | GAA (0.45) | CYP1A2CYP3A4POLBALDH1A1PARP1 | |
| SCHEMBL3020104 | 0.83 | KDR (0.60) | KDRNPC1RAB9ACYP2D6CYP2C9 | |
| SCHEMBL3007286 | 0.83 | KDR (0.60) | KDRNPC1RAB9ACYP2D6CYP2C9 | |
| SCHEMBL29791629 | 0.83 | MEN1 (0.41) | NPC1RAB9APOLBTP53MAPK1 | |
| SCHEMBL1757402 | 0.80 | HTT (0.33) | KDRNPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046279-B1 | Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of uv radiation and cosmetic compositions thereof | BASF SE (DE) | 2014-05-14 | — | — | EP | disclosed |
| US-8221729-B2 | Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of UV radiation and cosmetic compositions thereof | BASF SE (DE) | 2012-07-17 | — | — | US | disclosed |
| US-20090246154-A1 | USE OF AMINOPHENYLBENZOTRIAZOLE DERIVATIVES FOR PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE HARMFUL EFFECTS OF UV RADIATION AND COSMETIC COMPOSITIONS THEREOF | BASF SE (DE) | 2009-10-01 | — | — | US | disclosed |
| EP-2046279-A1 | USE OF AMINOPHENYLBENZOTRIAZOLE DERIVATIVES FOR PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE HARMFUL EFFECTS OF UV RADIATION AND COSMETIC COMPOSITIONS THEREOF | Ciba Holding Inc. (CH) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012304-A1 | USE OF AMINOPHENYLBENZOTRIAZOLE DERIVATIVES FOR PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE HARMFUL EFFECTS OF UV RADIATION AND COSMETIC COMPOSITIONS THEREOF | CIBA HOLDING INC. (CH) | 2008-01-31 | — | — | WO | disclosed |
| WO-2001012150-A1 | COSMETIC COMPOSITIONS WITH THERMOCHROMIC COLOR CHANGE SUBSTANCES AND AN AGENT FOR INDUCING A TEMPERATURE CHANGE | UNILEVER PLC (GB) | 2001-02-22 | — | — | WO | disclosed |
| WO-2001012149-A1 | COSMETIC STRIPS WITH TEMPERATURE DEPENDENT COLOUR CHANGE | UNILEVER PLC (GB) | 2001-02-22 | — | — | WO | disclosed |
| US-4865648-A | ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE | KITO TSUTOMU (JP) | 1989-09-12 | — | — | US | disclosed |
| US-4732810-A | CONTAINING ESTERS WITH SPECIFIC MELTING POINT-CLOUD POINT VALVE; LOW HYSTERESIS | PILOT INK CO., LTD. (JP) | 1988-03-22 | — | — | US | disclosed |
| US-4720301-A | Reversible heat sensitive recording composition | PILOT INK CO., LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| US-4717710-A | CHROMOGEN, TRIAZOLE, AZOMETHINE OR CARBOXYLIC ACID AMINE SALT, AND AN ALCOHOL, AMIDE OR ESTER SOLVENT | MATSUI SHIKISO CHEMICAL CO. LTD. (JP) | 1988-01-05 | — | — | US | disclosed |
| EP-0188635-A1 | Thermochromic composition | MATSUI SHIKISO CHEMICAL CO., LTD (JP) | 1986-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246154-A1 | USE OF AMINOPHENYLBENZOTRIAZOLE DERIVATIVES FOR PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE HARMFUL EFFECTS OF UV RADIATION AND COSMETIC COMPOSITIONS THEREOF | C9, C5, C3AR1 | KDR 3653/4885PSMB8 1441/4885NPC1 3087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.