Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970651 | 0.83 | STS (1.00) | STS | |
| SCHEMBL3222306 | 0.83 | STS (0.72) | STSMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL28418216 | 0.81 | STS (0.90) | STS | |
| SCHEMBL22089505 | 0.81 | STS (0.90) | STS | |
| SCHEMBL4990110 | 0.80 | STS (0.62) | STSMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL13006880 | 0.79 | NPSR1 (0.67) | MAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL1967952 | 0.78 | STS (0.58) | STSALDH1A1HPGDP2RY12CYP3A4 | |
| SCHEMBL3328561 | 0.77 | STS (0.81) | STSP2RY12 | |
| Hydrochloric Acid SCHEMBL4875114 | 0.76 | STS (0.57) | STSALDH1A1HPGDP2RY12CYP3A4 | |
| SCHEMBL21569748 | 0.75 | CYP2C19 (0.58) | MAPTALDH1A1HPGDCYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044050-A1 | NEW PYRIDINE ANALOGUES | Astra Zeneca AB (SE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008004946-A1 | NEW PYRIDINE ANALOGUES | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | disclosed |