Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ARG2 | P78540 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327534 | 1.00 | MAOB (0.52) | MAOBCA1CA2ARG2TP53 | |
| SCHEMBL9327526 | 1.00 | MAOB (0.52) | MAOBCA1CA2ARG2TP53 | |
| SCHEMBL1586710 | 0.85 | MAOB (0.52) | MAOBCA1CA2ARG2TP53 | |
| SCHEMBL6891100 | 0.85 | MAOB (0.52) | MAOBCA1CA2ARG2TP53 | |
| SCHEMBL25228665 | 0.83 | MAOB (0.50) | MAOBCA1CA2ARG2TP53 | |
| Ammonia Solution, Strong SCHEMBL27544194 | 0.83 | MAOB (0.50) | MAOBCA1CA2ARG2TP53 | |
| SCHEMBL7449629 | 0.81 | MAOB (0.48) | MAOBCA1CA2ARG2TP53 | |
| SCHEMBL24139370 | 0.81 | MAOB (0.48) | MAOBCA1CA2ARG2TP53 | |
| SCHEMBL96316 | 0.81 | MAOB (0.48) | MAOBCA1CA2ARG2TP53 | |
| SCHEMBL7449621 | 0.81 | MAOB (0.48) | MAOBCA1CA2ARG2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043644-A1 | NF- B INHIBITOR | Otsuka Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008010601-A1 | NF- ϰB INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | WO | disclosed |
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0719258-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996002508-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |
| US-5312950-A | Method for purification of alcohols | EASTMAN KODAK COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-4080388-A | Phenyl substituted-hexene-(3)-diol-(1,6) | STUDIENGESELLSCHAFT KOHLE MBH (DT) | 1978-03-21 | — | — | US | disclosed |
| US-3954887-A | PHENYL SUBSTITUTED UNSATURATED DIOLS | STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) | 1976-05-04 | — | — | US | disclosed |