Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780729 | 0.88 | CHRNA7 (0.63) | CHRNA7 | |
| SCHEMBL3930471 | 0.88 | CHRNA7 (0.59) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL779362 | 0.87 | KCNH2 (0.64) | CHRNA7 | |
| SCHEMBL780408 | 0.87 | CHRNA7 (0.61) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL780610 | 0.86 | KCNH2 (0.62) | CHRNA7 | |
| SCHEMBL782114 | 0.85 | CHRNA7 (0.57) | CHRNA7 | |
| SCHEMBL778207 | 0.85 | CHRNA7 (0.61) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL780466 | 0.84 | KCNH2 (0.58) | — | |
| Hydrochloric Acid SCHEMBL780175 | 0.84 | KCNH2 (0.62) | CHRNA7 | |
| SCHEMBL780281 | 0.83 | CHRNA7 (0.75) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044038-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | Cornerstone Therapeutics Inc. (US) | 2009-04-08 | — | — | EP | claimed |
| WO-2007146066-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | CRITICAL THERAPEUTICS, INC. (US) | 2007-12-21 | — | — | WO | claimed |