Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331640 | 0.79 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL1333476 | 0.78 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL1333649 | 0.76 | TSHR (0.52) | PTGDR2 | |
| SCHEMBL1331691 | 0.76 | TSHR (0.52) | PTGDR2 | |
| SCHEMBL1333478 | 0.76 | PTGDR2 (0.45) | PTGDR2AVPR2GPR27 | |
| SCHEMBL1331693 | 0.76 | TSHR (0.52) | PTGDR2 | |
| SCHEMBL4768117 | 0.74 | PTGDR2 (0.42) | PTGDR2PTGS2FAAHKCNH2 | |
| SCHEMBL1333474 | 0.74 | TSHR (0.39) | PTGDR2AVPR2GPR27PKMMCOLN3 | |
| SCHEMBL2281930 | 0.74 | PTGDR2 (0.40) | PTGDR2AVPR2GPR27FAAHKCNH2 | |
| SCHEMBL1331687 | 0.73 | MEN1 (0.56) | PTGDR2AVPR2GPR27PTGS2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660431-B1 | PHENOXYACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | disclosed |